Fever in the Returning Traveler

Huang, Felicia A Scaggs; Schlaudecker, Elizabeth P.

doi:10.1016/j.idc.2017.10.009

Cited by 12 publications

(10 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Diagnosis of febrile illnesses in travelers and people living in areas endemic for mosquito-borne diseases is a global challenge. There is a highly diverse group of etiological agents and diseases to consider, such as malaria, dengue, and enteric fevers [ 1 ]. Several of the mosquito-borne microbes are clinically important viruses, such as dengue (DENV), Zika (ZIKV), West Nile (WNV), and chikungunya viruses (CHIKV).…”

Section: Introductionmentioning

confidence: 99%

Chikungunya virus infections in Finnish travellers 2009-2019

Jääskeläinen

Kareinen

Smura

et al. 2020

Infection Ecology & Epidemiology

View full text Add to dashboard Cite

The mosquito-borne chikungunya virus (CHIKV) causes an acute febrile illness with rash, joint and muscle pain.A realtime RT-PCR assay for CHIKV detecting non-structural protein (nsP2; CHIKV nsP2-RT-qPCR) was set up. All the serodiagnosed CHIKV cases detected during 2009-2019 in Finland were screened with the assay, followed by isolations attempts and sequencing using Sanger and next generation sequencing (NGS). To validate the assay external and in-house quality control samples were used and all were correctly identified. Specificity of the assay was 100%. Assay was sensitive to detect CHIKV RNA in dilution of 10-8 .During years 2009-2019 34 patients were diagnosed for acute CHIKV infection. Twelve out of 34 cases were positive by CHIKV nsP2-RT-qPCR.Two CHIKV isolations succeeded from two individuals infected originally in Thailand, 2019. From 12 CHIKV nsP2-RT-qPCR positive samples, five (42%) CHIKVs were successfully sequenced. In this study, CHIKVs from year 2019 clustered with CHIKV ECSA-lineage forming sub-cluster with strains from ones detected in Bangladesh 2017, and the ones from Jamaica (2014) within Asian lineage showing highest similarity to strains detected in Caribbean outbreak 2013-15. Majority of the CHIKV infections detected in Finland originates from Asia and virus lineages reflect the global circulation of the pathogen.

show abstract

Section: Introductionmentioning

confidence: 99%

Chikungunya virus infections in Finnish travellers 2009-2019

Jääskeläinen

Kareinen

Smura

et al. 2020

Infection Ecology & Epidemiology

View full text Add to dashboard Cite

show abstract

“…41 The majority of imported cases of malaria in the USA and European countries occur among immigrants and VFR travelers. 7 , 8 Children account for 11% to 23% of cases of imported malaria and the majority were associated with travel to Sub-Saharan Africa. 7 VFR children have 4 times higher risk of getting malaria than tourists.…”

Section: Major Tropical Causes Of Fevermentioning

confidence: 99%

“…It also should be considered in those who fail to improve with antibiotics for presumed bacterial pneumonia. 8 Children younger than 4 years of age are at risk of disseminated infection which may manifest as miliary tuberculosis or TB meningitis. Drug-resistant MTB is an increasing problem in different parts of the world.…”

Section: Major Tropical Causes Of Fevermentioning

confidence: 99%

See 1 more Smart Citation

Fever in the Returned Pediatric Traveler

Abdel‐Haq

Asmar

2021

Global Pediatric Health

View full text Add to dashboard Cite

Global mobility has been steadily increasing in recent years. The assessment of the febrile child returning from international travel is a diagnostic challenge. The COVID-19 pandemic has profoundly affected international travel and made evaluation and management of the sick returned traveler more challenging. Children visiting friends and relatives abroad remain at higher risk of infection compared to tourists. This review presents a guidance on the initial assessment of a traveling febrile child including interpretation of medical history, physical examination, and laboratory findings. Important clues to etiology include exposure to different infectious agents, incubation periods of pathogens, and prophylaxis regimens and vaccines received. Early identification of potentially life-threatening and highly contagious infections is essential. In this article, we discuss the epidemiology, evaluation, and management of specific travel related infections such as malaria, typhoid fever, dengue fever, viral hemorrhagic fever, rickettsiosis, leptospirosis, schistosomiasis, gastrointestinal, and respiratory infections.

show abstract

“…Studies from other centres confirm that the most frequent diseases observed at arrival are dermatological conditions. Up to 70% of adoptees manifest at least one skin disease of which 57% are infectious .…”

mentioning

confidence: 99%