Fetuin-A, Preptin, and Ceruloplasmin: A Possible Link Between Chronic Periodontitis and Diabetes Mellitus: A Review

Abstract

Chronic periodontitis (CP) is a common inflammatory disease which is characterized by progressive destruction of the tooth supporting structures and ultimately, potential tooth loss. A relationship between CP and diabetes has been recognized for some time. Both diseases share several collective risk factors, however, recent research has provided greater insight into the relationship with evidence emerging for each disease being a co-factor in the pathogenesis of the other. This article focuses on some biochemical markers as valuable utility in risk assessment, clinical screening, diagnosis, and prognosis prediction of chronic periodontitis and diabetes mellitus