Feto-maternal haemorrhage in therapeutic abortion

Voigt, J.; Britt, R P

doi:10.1136/bmj.4.5680.395

Cited by 31 publications

(7 citation statements)

References 8 publications

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“…The risk of FMH after pregnancy termination has been reported in several studies (Katz 1969;Queenan et al 1971;Voigt & Britt 1969). The high frequency of fetomaternal transfusions found in this study corresponds with the data reported by Queenan et al (1971) In pregnancies terminated at 16 and 17 weeks we found a dip in the frequency of FMH as indicated by either a positive Kleihauer test or a raised AFP level.…”

Section: Discussionsupporting

confidence: 92%

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Elevation of maternal α–fetoprotein serum levels in relation to fetomaternal haemorrhage after second trimester pregnancy termination by aspirotomy

Gravenhorst

Beintema-Dubbeldam

Lith³

et al. 1986

BJOG

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Section: Discussionsupporting

confidence: 92%

“…After the operation fetal cell scores corresponding to a FMH of at least 0.1 ml were detected in Short communications 1303& Britt (1969 for second-trimester pregnancy termination. We have also confirmed that there is a progressive increase in the frequency of FMH with gestation.…”

Section: Resultsmentioning

confidence: 99%

Elevation of maternal α–fetoprotein serum levels in relation to fetomaternal haemorrhage after second trimester pregnancy termination by aspirotomy

Gravenhorst

Beintema-Dubbeldam

Lith³

et al. 1986

BJOG

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“…Several reports indicate that fetal erythrocytes may enter maternal cir culation in the course of induced abortion, even if done in the first trimester of pregnancy [2,4,5,7,11,13,16,24]. This statement is valid, although recent studies of Pembrey et al [21] have contested the reliability of estima tions on the amount of fetal blood absorbed through transplacental haemor rhage.…”

Section: Introductionmentioning

confidence: 66%

Efficiency of Anti-D IgG Prevention after Induced Abortion

Simonovits¹

1974

Vox Sanguinis

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In the years 1971-1972 a total of 8,986 Rh-negative women who underwent induced abortion in the first trimester of pregnancy were protected with 50 µg anti-D IgG. Among these were 2,419 primigravidae. Out of these, serological controls could be performed in 1,588 patients 3 or 6 months after abortion. The control has shown that 4 of the 1,588 protected primigravidae (0.25%) became immunized. Two of these proved to be positive only by the papain test. Anti-D prophylaxis diminishes immunization of the abortion recipient to about 1/20 when using the risk figures reported in the literature. Results of the prophylaxis and the observation that 38.0% of the women undergoing induced abortion are young (15-19 years old) justify the opinion of those who advocate administration of anti-D in induced abortion.

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“…The risein AFP is due to letomaternal haemorrhage: fetal levels of AEP are around a million-fold greater than maternal levels so that transfer ol' very small quantities of fctal blood can produce this phenomenon. 1971, Voigt & Britt 1969. 1971, Voigt & Britt 1969.…”

mentioning

confidence: 99%

“…Fetomaternal haemorrhage can also occur i n association with elective termination of pregnancy (Katz 1969, Queenan et ul. 1971, Voigt & Britt 1969) is a syntbctic 19-norsteroid which binds to the pi-ogesterone reccptor and therefore acts as an antagonist to the effects of progesterone on target cells (Baulieu 198%. b,Shaison et al 19%).…”

mentioning

confidence: 99%

Changes in circulating alphafetoprotein following administration of mifepristone in first trimester pregnancy

Chard

Olajide

Kitau

1990

BJOG

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T h e occurrence of fetoinaternal haemorrhage was investigated in 30 women by measuring inaternal scrum alphafetoprotein (AFP) levels before and after the administration of mifepristone (KU 486) for termination of first trimester pregnancy. A significant rise in AFP levels was ceen in 21 women (70'26), the increase ranging from 6 to 660% of bascline level?. The apparent frequency of fetomaternal haemorrhage was similar to that reported previously for surgical termination of first trimestcr pregnancies.

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Feto-maternal haemorrhage in therapeutic abortion

Cited by 31 publications

References 8 publications

Elevation of maternal α–fetoprotein serum levels in relation to fetomaternal haemorrhage after second trimester pregnancy termination by aspirotomy

Elevation of maternal α–fetoprotein serum levels in relation to fetomaternal haemorrhage after second trimester pregnancy termination by aspirotomy

Efficiency of Anti-D IgG Prevention after Induced Abortion

Changes in circulating alphafetoprotein following administration of mifepristone in first trimester pregnancy

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