Fetal tachycardia prior to the development of hydrops—Attempted pharmacologic cardioversion: Case report

Klein, Alan F.; Holzman, Ian R.; Austin, Edward M.

doi:10.1016/s0002-9378(16)33045-9

Cited by 52 publications

(14 citation statements)

References 2 publications

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“…Until 19 describing failure of treatment before the development of hydrops may indicate a more complicated mechanism in some cases. The transmission of verapanil across the placenta is variable,20 but verapamil was selected in this case in which the arrhythmia proved refractory to digitalis and procainamide.…”

Section: Methodsmentioning

confidence: 99%

Arrhythmia and structural abnormalities of the fetal heart.

Stewart¹,

Tonge²,

Wladimiroff³

1983

Heart

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suMMARY Thirty fetuses with cardiac arrythmias were referred for ultrasonography. This included cross sectional and M mode echocardiography and pulsed Doppler analysis of the fetal heart. Three types of arrhythmias were observed: ectopic beats, tachyarrhythmias, and bradycardia. Ectopic beats were associated with cardiac structural abnormalities in two cases, resulting in fetal death in one. Tachycardia was not associated with structural defect, but death from cardiac failure occurred in one patient. Transplacental treatment for tachyarrhythmia was not successful in our experience. In the group with bradycardia four cases had congenital cardiac abnormalities and the mortality rate was 50%.When a fetal cardiac arrhythmia has been established careful structural and rhythm analysis is of vital importance in facilitating prognosis, planning of time and mode of delivery, and monitoring of transplacental treatment where indicated.

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Section: Methodsmentioning

confidence: 99%

Arrhythmia and structural abnormalities of the fetal heart.

Stewart¹,

Tonge²,

Wladimiroff³

1983

Heart

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“…These technical approaches can obscure FHR monitor and falsely normal FHR is mimicked [5,7,8,13]. In this case, pre-excitation with bi-or trigeminal pulse caused severe tachycardia, but on the fetal monitor appeared a "normal" heart rate tracing (figure 2); or during the preceding and intrapartum periods of bi-and trigeminal pulse FHR was numerically normal, but a severe bradycardia was recorded (figures 1, and 4).…”

Section: Discussionmentioning

confidence: 91%

“…Apart from a hydropic placenta, ultrasound examination showed nor- mal fetal and cardiac anatomy, but with arrhythmia in fetal real-time and M-mode echocardiography [7,8]. The obtained FHR-record was irregular, showing alternating periods of severe bradycardia.…”

Section: Clinical Information and Resultsmentioning

confidence: 97%

Evaluation of fetal heart rate artifacts, hemodynamics and digoxin treatment in fetal tachyarrhythmia by Doppler measurement of fetal blood flow — case report of a pre-excitation syndrome

Gonser¹,

Dietl²,

Pfeiffer³

et al. 1989

Jpme

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“…In most reported cases digoxin was supplemented by drugs such as betamethasone, verapamil, propranolol, procainamide and quinidine [10,12,13,16,[17][18][19].…”

Section: Discussionmentioning

confidence: 99%

Successful Outcome of Idiopathic Nonimmune Hydrops Fetalis Treated by Maternal Digoxin

Chavkin

Kupfersztain²,

Ergaz³

et al. 1996

Gynecol Obstet Invest

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Nonimmune hydrops fetalis (NIHF), occurring in 1 in 2,500–3,000 live births, has a reported mortality rate of 50–98%. A similar mortality rate for intrauterine death of fetuses with NIHF probably exists. Many fetal pathological entities have been implicated as causing the condition, but to date, treatment has only been found for cases of fetal tachycardia complicated with hydrops. During a routine ultrasonographic survey of a woman at 32 weeks of gestation, we detected a fetus with severe ascites. There was no apparent etiology, and although no tachycardia was evident, low dosage transplacental digoxin therapy was immediately initiated. The hydropic condition completely resolved within 17 days, and at 39 weeks of gestation, a perfectly normal baby was born after a spontaneous and uneventful labor. This is the first report of successful treatment of idiopathic NIHF with maternal digoxin.

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Fetal tachycardia prior to the development of hydrops—Attempted pharmacologic cardioversion: Case report

Cited by 52 publications

References 2 publications

Arrhythmia and structural abnormalities of the fetal heart.

Arrhythmia and structural abnormalities of the fetal heart.

Evaluation of fetal heart rate artifacts, hemodynamics and digoxin treatment in fetal tachyarrhythmia by Doppler measurement of fetal blood flow — case report of a pre-excitation syndrome

Successful Outcome of Idiopathic Nonimmune Hydrops Fetalis Treated by Maternal Digoxin

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