Fetal middle cerebral artery peak systolic velocities in a local Indian scenario

Abstract

The results indicate that a local fetus would be anemic even before its MCA-PSV rises to the internationally accepted standard of fetal anemia. Hence, by the time the MCA-PSV value of the local fetus rises to the point where it is deemed severely anemic as per values mentioned in other published literature, it might be too late for intervention and the fetal health as well as life might be at stake. Each geographic locality should therefore develop its own standard values.

Performance of fetal middle cerebral artery peak systolic velocity for prediction of anemia in untransfused and transfused fetuses: systematic review and meta‐analysis

“…After review, 12 studies were retained for the analysis (Figure ). Characteristics of studies included in the meta‐analysis are given in Table and those of studies excluded are given in Appendix S2.…”

Fetal hypertrophic cardiomyopathy with elevated middle cerebral artery peak systolic velocity (MCA PSV): A potentially grim association

“… 7 One retrospective review at a single center from 2000 to 2012 found a transplantation‐free survival from diagnosis to 1 month and 1 year of life to be 35% and 18%, respectively. 8 To our knowledge, the association between hypertrophic cardiomyopathy and elevated MCA PSV has only been described once in the literature 3 with a cause of the hypertrophic cardiomyopathy identified. Specifically, that case was complicated by pre‐existing diabetes mellitus, with an ultimately favorable outcome.…”

“…2 An association between fetal hypertrophic cardiomyopathy and elevated MCA PSV has only been described once previously in a pregnancy, which was complicated by pregestational diabetes mellitus with the resolution of both findings postnatally. 3 Here we present two cases in the absence of pre‐existing or gestational diabetes with this association and ultimately poor neonatal outcomes.…”

“…Others have suggested that cardiomyopathy results in enhanced left ventricular contraction with the increased force of blood and likely elevation in MCA PSV. 3 In addition, the elevated MCA PSV may be related to fluid dynamics. The continuity equation of fluid dynamics states that the mass flow rate into the volume must equal the mass flow rate out of the volume.…”

“…There are a few possible explanations for this association. Others have suggested that cardiomyopathy results in enhanced left ventricular contraction with the increased force of blood and likely elevation in MCA PSV 3 . In addition, the elevated MCA PSV may be related to fluid dynamics.…”