Fetal macrosomia: risk factors and outcome

Bérard, Joël; Dufour, P.; Vinatier, D.; Subtil, D.; Vanderstichele, S; Monnier, Jean-Marie; Puech, F

doi:10.1016/s0301-2115(97)00242-x

Cited by 112 publications

(17 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study, hemorrhage, pregnancy-induced hypertension, and obstructed labor were the major maternal complications which may be associated with macrosomia. High BMI of mothers was significantly associated with delivering macrosomic neonates, which concurs with previous studies which showed the association of obesity and high BMI with macrosomic birth [3, 18, 19]. As Ethiopia is a developing country, we are beginning to be affected by the double burden of diseases with emerging chronic disease like obesity (high BMI) [35], hence a parallel increase in macrosomia is expected.…”

Section: Discussionsupporting

confidence: 86%

“…Based on birth weight, the World Health Organization (WHO) classifies infants as Low Birth Weight(LBW) (<2500 g), Normal birth weight (2500–4000), and Macrosomia (≥4000 g) [2, 3]. Evidence shows that pregnancies with macrosomic infants are associated with increased risk of complications for both the neonates and their mothers [4–6].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Low birth weight and macrosomia in Tigray, Northern Ethiopia: who are the mothers at risk?

et al. 2017

View full text Add to dashboard Cite

BackgroundInfant birth weight, which is classified into low birth weight, normal birth weight and macrosomia, is associated with short and long-term health consequences, such as neonatal mortality and chronic disease in life. Macrosomia and low birth weight are double burden problems in developing counties, such as Ethiopia, but the paucity of evidence has made it difficult to assess the extent of this situation. As a result there has been inconsistency in the reported prevalence of low birth weight and macrosomia in Ethiopia. This study aimed to determine the incidence and predictors of low birth weight and macrosomia in Tigray, Northern Ethiopia.MethodWe conducted a cross-sectional survey among a cohort of 1152 neonates delivered in Tigray Region at randomly selected hospitals between April and July 2014. We used the birth weight category described previously as an outcome variable. Data were collected using structured questionnaire by midwives. We entered and analyzed data using STATA™ Version 11.0. Data were described using a frequency, percentage, relative risk ratio, and 95% confidence interval. Multinomial logistic regression was conducted to identify independent predictors of low birth weight and macrosomia.ResultIn this study, we found a 10.5% and 6.68% incidence of low birth weight and macrosomia, respectively. Seventy (57.8%) of all low birth weight neonates were term births. The predictors for low birth weight were: early marriage (<18 year) (RRR: 0.59, CI: 0.35–0.97); rural residence (RRR: 0.53, CI: 0.32–0.9); prematurity (RRR: 15.4, CI: 9.18–25.9); no antenatal follow-up (RRR: 6.78, CI: 2.39–19.25); and female sex (RRR: 1.77, CI: 1.13–2.77). Predictors for macrosomia were: female gender (RRR: 0.58, CI: 0.35–0.9); high body mass index (RRR: 5.0, CI: 1.56–16); post-maturity (RRR: 2.23, CI: 1.06–4.6); and no maternal complication (RRR: 0.46, CI: 0.27–0.8).ConclusionIn this study, we found gestational age and gender of the neonate to be common risk factors for both low birth weight and macrosomia. Strengthening antenatal follow up, prevention of pre and post maturity, controlling body mass index, and improving socioeconomic status of mothers are recommendations to prevent the double burden (low birth weight and macrosomia) and associated short and long-term consequences.

show abstract

Section: Discussionsupporting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Low birth weight and macrosomia in Tigray, Northern Ethiopia: who are the mothers at risk?

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Similarly, previous studies demonstrated higher rates of shoulder dystocia among birth weight >4000 g [13] that increased significantly 3–4 times when the birth weight was >4500 g [6,7,14,16,19,20]. Our study demonstrated that the odds ratio for shoulder dystocia was similar in the 4000–4250 g group and the 4250–4500 g pregnancies (was 2.3 times higher compared to AGA pregnancies).…”

Section: Discussionsupporting

confidence: 86%

“…Similarly, Siggelkow et al and Lim et al, in their studies on birth weight >4000 g, and Berard et al in their study on >4500 g showed an overall rate of cesarean section of 27.4%. 43.9% and 36%, respectively [10,13,14]. Nevertheless, Raio et al and Navti et al presented smaller rates of overall cesarean section of 16.7% and 22.3%, respectively in the >4500 g group [15,16].…”

Section: Discussionmentioning

confidence: 99%

Maternal and neonatal outcomes of macrosomic pregnancies

et al. 2012

View full text Add to dashboard Cite

SummaryBackgroundTo compare maternal and neonatal outcomes of term macrosomic and adequate for gestational age (AGA) pregnancies.Material/MethodsA retrospective analysis was performed on all term singleton macrosomic (birth weight ≥4000 g) and AGA (birth weight >10th percentile and <4000 g) pregnancies delivered at our hospital between 2004 and 2008. Data collected included maternal age, gestational age at delivery, mode of delivery, birth weight, fetal gender, maternal and neonatal complications. Comparisons were made between macrosomic and AGA pregnancies and between different severities of macrosomia (4000–4250 g, 4250–4500 g and ≥4500 g).ResultsThe study population comprised of 34,685 pregnancies. 2077 neonates had birth weight ≥4000 g. Maternal age and gestational age at delivery were significantly higher for macrosomic neonates. Significantly more macrosomic neonates were born by cesarean section, and were complicated with shoulder dystocia, neonatal hypoglycemia, and had longer hospitalization period (both in vaginal and cesarean deliveries). Specifically, the odds ratio (OR) relative to AGA pregnancies for each macrosomic category (4000–4250 g, 4250–4500 g and ≥4500 g) of shoulder dystocia was 2.37, 2.24, 7.61, respectively, and for neonatal hypoglycemia 4.24, 4.41, 4.15, respectively. The risk of post partum hemorrhage was statistically increased when birth weight was >4500 g (OR=5.23) but not for birth weight between 4000–4500 g. No differences were found in the rates of extensive perineal lacerations between AGA and the different macrosomic groups.ConclusionsMacrosomia is associated with increased rate of cesarean section, shoulder dystocia, neonatal hypoglycemia, and longer hospitalization, but not associated with excessive perineal tears. Increased risk of PPH was found in the >4500g group.

show abstract

“…9,[16][17][18][22][23][24][25][26][27][28][29][30][31] The roles of episiotomy and maternal age have previously not been clearly defined. Episiotomy is perhaps the most frequently performed operative procedure during delivery.…”

Section: Discussionmentioning

confidence: 99%