Fetal hypoxia: Temperature value for oxygen exchange, resistance to hypoxic damage, and diagnostics using a thermal imager

Urakov, Aleksandr; Уракова, Н. А.

doi:10.18231/j.ijogr.2020.048

Cited by 8 publications

(5 citation statements)

References 20 publications

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“…It should be recognized that about 10 years have passed since the publication of these facts, but neither women nor obstetricians That is why women do not know the truth that their uterus during contractions compresses the blood vessels inside itself, that this inevitably causes transient ischemia of both the uterus and placenta, and also causes fetal hypoxia [14,15].…”

Section: Resultsmentioning

confidence: 99%

Low Value of Apnea-test on Fetal Survival in Intrauterine Hypoxia is Universal Indicator for Planned Caesarean Section

Уракова¹,

Ураков²

2020

Act Sci wom hea

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The review is devoted to the justification of apnea-test on fetal survival for hypoxia in a pregnant woman as a criterion for choosing the type of planned delivery through the natural birth canal or by Cesarean section. It is shown that during physiological childbirth in women, the uterus repeatedly worsens the blood supply to the placenta, which causes intrauterine hypoxia of the fetus at each contraction. This is because during contractions, the uterus squeezes not only the fetal bladder with amniotic fluid and the fetus, but also the placenta, as well as blood vessels that are located inside the uterine wall and through which arterial blood flows to the placenta. Therefore, when giving birth through the natural birth canal, the fetus is forced to repeatedly experience periods of hypoxia. However, the ability of fetuses to survive periods of intrauterine hypoxia in future births today is not taken into account when choosing the type of delivery. It has been shown that apnea-test on fetal survival at hypoxia can increase the accuracy of choosing the planned type of birth resolution. It has been established that if the period of immobility of the fetus during respiratory retention by its mother is less than 10 seconds, then childbirth through the natural birth canal is contraindicated, since this can cause drowning of the fetus in amniotic fluid, asphyxia, encephalopathy and pneumonia of the newborn. Planned Caesarean section can improve the prognosis of childbirth.

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Section: Resultsmentioning

confidence: 99%

Low Value of Apnea-test on Fetal Survival in Intrauterine Hypoxia is Universal Indicator for Planned Caesarean Section

Уракова¹,

Ураков²

2020

Act Sci wom hea

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“…[26]. Тем не менее в настоящее время в медико-биологических исследованиях лидерство занимают рыбки данио рерио (Danio rerio или Zebrafish) [54][55][56][57][58].…”

Section: аквариумные рыбки как инструмент для высокоточной температур...unclassified

Aquarium fish and temperature neuropharmacology: Update

Urakov,

Fisher,

Lebedev

et al. 2024

Psychopharmacology & biological narcology

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It is shown that at the end of the 20th century in Russia studies of temperature dependence of specific pharmacological activity of antihypoxants and some neurotropic drugs under normo- and hypothermia of various biological objects in experimental and clinical conditions were started. At the beginning of the 21st century, an original biological model of acute hypoxia in aquarium fish was developed. This model made it possible to start the study of fish resistance to hypoxia, to screen biologically active substances and to evaluate the activity of antihypoxants under normo- and hypothermia. The first results of using this model allowed to conclude that the dynamics of motor activity of fish under conditions of acute hypoxia is similar to the dynamics of motor activity of fetuses inside the uterus under diagnostic intrauterine hypoxia created by voluntary apnea in a pregnant woman. It was found that the value of the duration of the period of immobile state of fish and fetuses under hypoxia is directly proportional to the value of their resistance to hypoxia. It was found that the reduction in conditions of acute hypoxia water temperature with floating fish in it on 10 °C lengthens the duration of the period of immobile state of fish and the period of preservation of their viability more than 2 times, and the preliminary introduction of hydrogen peroxide in the water in the therapeutic dose in combination with hypothermia lengthens the corresponding periods by 4 times. It has also been found that such neurotropic drugs as ethyl alcohol, local and general anesthetics will completely eliminate the pain syndrome that develops during local hypothermia in normal. In addition, it has been shown that immersing the hands of people under alcohol intoxication and/or surgical anesthesia in water with melting ice for 2 minutes eliminates the feeling of pain in the hands and accelerates the development of subsequent hyperemia in the skin of the hands by 2 times compared to the norm.

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“…Drug irritation can be assessed by local tissue inflammation at the injection sites, and inflammation can be assessed by local temperature dynamics. Modern thermal imaging cameras and their use in biology and medicine allow infrared thermography to detect local inflammation at injection sites in real time [ [52] , [53] , [54] , [55] , [56] ].…”

Section: Introductionmentioning

confidence: 99%

Thermal imaging of local skin temperature as part of quality and safety assessment of injectable drugs

Urakov,

Urakova,

Samorodov

et al. 2024

Heliyon

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Fetal hypoxia: Temperature value for oxygen exchange, resistance to hypoxic damage, and diagnostics using a thermal imager

Cited by 8 publications

References 20 publications

Low Value of Apnea-test on Fetal Survival in Intrauterine Hypoxia is Universal Indicator for Planned Caesarean Section

Low Value of Apnea-test on Fetal Survival in Intrauterine Hypoxia is Universal Indicator for Planned Caesarean Section

Aquarium fish and temperature neuropharmacology: Update

Thermal imaging of local skin temperature as part of quality and safety assessment of injectable drugs

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