Fetal heart rate and acid-base status in the assessment of fetal hypoxia

Wood, Carl; Ferguson, Russell S.; Leeton, John; Newman, Warwick; Walker, Adrian M.

doi:10.1016/0002-9378(67)90133-0

Cited by 63 publications

(21 citation statements)

References 5 publications

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“…Due to early methodological difficulties the results are not adequate to perm it firm conclusions; however, they generally confirm those published by Wood et al [7].…”

Section: (3) Short Term Bradycardiasupporting

confidence: 55%

Foetal Heart Frequency and Perinatal Condition of the Foetus and Newborn

Hammacher¹,

Hüter²,

Bokelmann³

et al. 1968

Gynecol Obstet Invest

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“…Due to early methodological difficulties the results are not adequate to perm it firm conclusions; however, they generally confirm those published by Wood et al [7].…”

Section: (3) Short Term Bradycardiasupporting

confidence: 55%

Foetal Heart Frequency and Perinatal Condition of the Foetus and Newborn

Hammacher¹,

Hüter²,

Bokelmann³

et al. 1968

Gynecol Obstet Invest

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“…The reliability of FSB sampling was not determined. In two studies [16,19] in which continuous electronic fetal monitoring was used, it was unclear as to which specific FHR changes constituted criteria for FSB sampling. In all studies reviewed, the scalp pH result may have influenced the clinical man agement of patients.…”

Section: Methodological Reviewmentioning

confidence: 99%

“…The definition of fetal acidosis varied from a pH of < 7.20 [ 19] to a pH of ^ 7.25 [16] and this variation may affect the comparability of the results. The reliability of FSB sampling was not determined.…”

Section: Methodological Reviewmentioning

confidence: 99%

Association between Indicators of Perinatal Asphyxia and Adverse Outcome in the Term Infant: A Methodological Review

Bryce¹,

Halperin

Sinclair

1985

Neuroepidemiology

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There are conflicting opinions about the significance of 5 perinatal findings felt to be indicators of asphyxia (meconium staining of the amniotic fluid, abnormal fetal heart rate patterns, acidotic fetal scalp blood gases, low Apgar scores, and acidotic cord blood gases). A review of the literature was undertaken to determine the strength of association of each of these findings with adverse outcomes. Although all studies contained methodological problems, these indicators were found to have strong associations with one or more adverse outcomes such as perinatal death, low Apgar scores or cerebral palsy. The strength of the association (relative risk) was found to vary inversely with the prevalence of the outcome.

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“…Fetal distress in the human results in numerous physiologic changes; included among these are decreased or absent fetal breathing movements and decreased heart rate with loss of beat-to-beat heart rate variability [16,24]. Little is known about changes in the electrocorticogram during human fetal distress.…”

Section: Introductionmentioning

confidence: 99%

Phenyl Isopropyl Adenosine Alters Fetal Electrocorticogram, Breathing and Heart Rate

Smith¹,

Pryor²,

Toubas³

et al. 1986

Dev Pharmacol Ther

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Six fetal sheep were equipped with intratracheal, amniotic and vascular catheters and electrocorticogram electrodes to study the effect of phenyl isopropyl adenosine (PIA) on electrocorticogram and fetal breathing movements. Three animals had functioning electrocardiogram electrodes. During 1,000-min control periods, low-voltage high- frequency (LVHF) electrocorticogram predominated 60 ± 1 % (mean ± SEM) of total time. Fetal breathing movements occurred 34 ± 1 % of total time and only during LVHF electrocorticogram. PIA 0.125 mg was given intravenously to the fetus during established LVHF electrocorticogram and fetal breathing movements. LVHF electrocorticogram converted in 58 ± 16 s to high-voltage low-frequency (HVLF) electrocorticogram which persisted for 10 ± 3 min. This was followed by a third electrocorticogram pattern for 119 ± 12 min. Fetal breathing movements ceased in 47 ± 25 s and did not recur for 150 ± 20 min. An increase in fetal breathing movements (59 ± 2% of total time) occurred between 300 and 800 min (control 34 ± 1 %, p < 0.05). Electrocardiogram demonstrated a decrease in heart rate from 170 ± 6 to 90 ± 6 beats per min with return to baseline in 113 ± 49 min. No significant changes occurred in blood gases. We conclude that fetal electrocorticogram, fetal breathing movements and heart rate are influenced by adenosine.

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Fetal heart rate and acid-base status in the assessment of fetal hypoxia

Cited by 63 publications

References 5 publications

Foetal Heart Frequency and Perinatal Condition of the Foetus and Newborn

Foetal Heart Frequency and Perinatal Condition of the Foetus and Newborn

Association between Indicators of Perinatal Asphyxia and Adverse Outcome in the Term Infant: A Methodological Review

Phenyl Isopropyl Adenosine Alters Fetal Electrocorticogram, Breathing and Heart Rate

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