Fetal Hand Abnormalities in the First-Trimester Scan: A Report of Two Cases

Abstract

Two cases of fetal hand abnormalities are presented in this report. The first one is a case of unilateral fetal syndactyly detected in the first trimester routine scan, resulting in the early diagnosis of a severe genetic condition by invasive testing and early termination of pregnancy. By doing so, we ensured that the woman was managed in the most appropriate way. In the second case, we describe a fetus with bilateral hand polydactyly, which was combined with a cardiac defect -incompatible with extrauterine life. This was once again diagnosed during the first trimester scan. An uncomplicated termination of pregnancy was achieved in the first trimester of pregnancy.

Prenatal Diagnosis of Williams-Beuren Syndrome Based on Suspected Fetal Hypotonia in Early Pregnancy

“…This could serve as the basis for informed choices and possibly early termination of pregnancy, which in many cases is the optimal choice. Early rather than late termination can be the optimal management in terms of women's health, both physically and from a psychological perspective [1,2,3].…”