Fetal Cystic Hygroma and Turner's Syndrome

Carr, Robert F.

doi:10.1001/archpedi.1986.02140200090035

Cited by 14 publications

(14 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cystic hygroma can be associated with congenital disorders including Turner syndrome, chromosomal aneuploidy, hydrops fetalis, Down syndrome and other trisomies, fetal alcohol syndrome, and Noonan syndrome [5,10] . Particularly, in 50-80% of patients affected by nuchal cystic hygromas, karyotypic abnormalities and various malformation syndromes are present.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Prenatal Diagnosis of a Fetal Chest Wall Cystic Lymphangioma Using Ultrasonography and MRI: A Case Report with Literature Review

et al. 2005

View full text Add to dashboard Cite

A case of fetal chest wall cystic lymphangioma diagnosed prenatally at 28 weeks’ gestation is reported. Ultrasound examination showed a multilocular, large cystic mass (10 × 22 × 29 mm) on the left side of the fetus in the area of the lower chest and upper abdomen, without color flow imaging. Magnetic resonance imaging was used to evaluate the extent and the tissue characteristics of the lesion. Two months after birth the lymphangioma was surgically removed, following an infection and a rapid increase in size. The case is discussed, and a short review of the literature is reported.

show abstract

Section: Discussionmentioning

confidence: 99%

“…There is a high prevalence of associated chromosomal abnormalities [5] .The success of surgical intervention, and the neonatal outcome mainly depends on the size, the location, and the type of the tumor [2] . In addition, prenatal diagnosis is important for a prompt and appropriate management.…”

mentioning

confidence: 99%

Prenatal Diagnosis of a Fetal Chest Wall Cystic Lymphangioma Using Ultrasonography and MRI: A Case Report with Literature Review

et al. 2005

View full text Add to dashboard Cite

show abstract

“…Byrne et al [2] and Carr et al [9] exam ined spontaneously aborted fetuses with cys tic hygromata and suggested that generalised edema represents strong phenotypic evi dence of Turner's syndrome. Thus, all 6 of their fetuses with edema had Turner's syn drome; in contrast 3 of the non-hydropic fetuses had normal karyotype and 1 had tri somy 21.…”

Section: Discussionmentioning

confidence: 99%

Fetal Nuchal Cystic Hygromata: Associated Malformations and Chromosomal Defects

et al. 1991

View full text Add to dashboard Cite

During a 6-year period (1985–1990), blood karyotyping was performed in 44 fetuses with septated, bilateral, dorsal, cervical cystic hygromata. This condition constitutes a different entity from nuchal oedema. There were 33 (75%) chromosomal abnormalities, including Turner’s syndrome (n = 31), trisomy 18 (n = 1) and trisomy 21 (n = 1). Congenital heart defects (CHD), mainly coarctation of the aorta, were present in 15 of the fetuses with Turner’s and in 1 of the chromosomally normal fetuses. The incidence of CHD was higher in the fetuses with ultrasonographic evidence of moderate/severe hydrops (41%; 13 of 32 cases) than in those with mild or no hydrops (25%; 3 of 12 cases). Although both the biparietal diameter (BPD) and femur length (FL) were reduced in all fetuses, the FL to BPD ratio was below the 5th percentile in 29 of the 33 (88 %) chromosomally abnormal fetuses, but in only 4 of the 11 (36%) chromosomally normal ones. In the chromosomally normal group, 3 of the fetuses had multiple pterygium syndromes, and in such cases the risk of recurrence may be high. In contrast, in the group of mutant chromosomal disorders with monosomy or trisomy, the risk of recurrence is in the order of 1%

show abstract

“…4 -11 They have been described as intrauterine tumors in fetuses, usually in association with Turner syndrome and other cytogenetic abnormalities. [12][13][14][15][16] A small number of cystic hygromas have also been described in children and adult patients in locations other than the neck, such as the mediastinum, heart, lung, chest wall, breast, greater omentum, retroperitoneum, small bowel mesentery, colon, axilla, cauda equina, and extremities. 11,17-26 Tricoire and associates 27 described 8 cases of familiar cystic hygroma involving 3 families.…”

Section: Discussionmentioning

confidence: 99%

Giant Cystic Hygroma of the Thymus in a Child

Marchevsky¹,

Rausei-mills²,

Hui³

2006

Pathology Case Reviews

View full text Add to dashboard Cite

A 4-year-old asymptomatic boy was found to have a large multicystic mass occupying the anterior mediastinum and approximately 80% of the left chest cavity. The lesion was resected and consisted of a large cystic hygroma measuring 18.0 cm in largest dimension, involving the thymus and the adjacent mediastinal soft tissues. The multicystic spaces were filled with straw-colored fluid, consistent with old hemorrhage, and were lined by endothelial-lined vascular spaces showing smooth muscle bundles and patchy lymphoid aggregates in their walls. Focal areas of stromal calcification were present. No teratomatous elements were identified within the mass. The patient recovered fully from the surgical procedure. Cystic hygromas (cystic lymphangiomas) are unusual tumors in children that usually develop in the neck but have been described in the thorax, abdomen, extremities, and other locations. Approximately 10% of cervical cystic hygromas extend to the mediastinum, but primary mediastinal lymphangiomas are extremely rare neoplasms that have been described mostly in fetuses and a few children and adult patients. The clinicopathologic findings of this unusual case and the differential diagnosis of mediastinal cysts in young children are discussed.

show abstract

Fetal Cystic Hygroma and Turner's Syndrome

Cited by 14 publications

References 18 publications

Prenatal Diagnosis of a Fetal Chest Wall Cystic Lymphangioma Using Ultrasonography and MRI: A Case Report with Literature Review

Prenatal Diagnosis of a Fetal Chest Wall Cystic Lymphangioma Using Ultrasonography and MRI: A Case Report with Literature Review

Fetal Nuchal Cystic Hygromata: Associated Malformations and Chromosomal Defects

Giant Cystic Hygroma of the Thymus in a Child

Contact Info

Product

Resources

About