Fetal Autopsy Study Over a Two Year Period

Prabhala, Shailaja; Korti, Padmaja; Erukkambattu, Jayashankar; Tanikella, Ramamurti

doi:10.14260/jemds/2015/328

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…3 A degree of cord twisting is normal but with excessive twisting, the protective effects are lost, and the risk of fetal hypoxia abounds. 11,12 In literature, there are studies stating that long cords are associated with greater incidence of hyper coiling and twisting of cords. Which is correlating with our study although the incidence of long cords in our study is minimal and presence of hyper coiling is also evident in short cord's as well.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of role of umbilical cord anomalies in fetal death-An institutional experience

Begum¹,

Mounika

Pavane³

et al. 2022

JDPO

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Umbilical cord plays pivotal role in development and well being of fetus. Any abnormality in the umbilical cord can affect the viability of the fetus. In spite of presence antenatal diagnostic modalities still fetal autopsy plays a vital role in identification and confirmation of the abnormalities which lead to intrauterine fetal death. To check for incidence of variety of cord abnormalities in perinatal fetal deaths. It is a retrospective observational study of 26 cases of perinatal deaths due to cord abnormalities taken from Jan 2013 to July 2021 in tertiary care center. In the study 26 cases of fetal autopsy were included over a period of nine years. Mean maternal age was 26 years. 12 cases (44.3%) were of vessel number defects. In which 11 were two vessel cords and the other was 5 vessel cord, 14 cases showed short cord. 8 cases showed normal cord length. 4 cases showed long cords. True knots were seen in one case. 3 cases (28%) were involving stenosed cords. and 5 cases (28.4%) were of supercoiling 3 twisted cords. Maternal co-morbidities were present in 3 cases.Umbilical cord anomaly is a major stress factor for fetus playing a key role in feto-maternal perfusion. Cord abnormalities can be clinically insignificant or can be severe leading to foetal death. The present study reemphasizes the importance of umbilical cord and its impact on wellbeing of foetus. Thus there is need to develop special and exclusive antenatal screening for umbilical cord abnormalities needs further research.

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Section: Discussionmentioning

confidence: 99%

Evaluation of role of umbilical cord anomalies in fetal death-An institutional experience

Begum¹,

Mounika

Pavane³

et al. 2022

JDPO

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“…A Belgian study found that it is feasible as early as 11 weeks' gestation (74). One study found that ultrasound findings were consistent with autopsy findings in 86.7% of cases (79), while another study found that autopsy confirmed the prenatal ultrasound findings in 50% of cases and changed the primary diagnosis in 9.09% of cases (80). In adults, PM-US can evaluate various pathological conditions in the body such as cardiac hypertrophy, liver metastasis, renal cysts, and intracranial hemorrhage in infants (72).…”

Section: Postmortem Ultrasoundmentioning

confidence: 96%

Virtopsy as a Breakthrough in Non-Invasive Autopsy: Its Principles and Potential of Application in Developing Countries During the Covid-19 Pandemic

Habiburrahman,

Wardoyo,

Yudhistira

2023

JUMMEC

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Autopsy practice is often limited due to the risk of infection transmission and family objections. As an alternative, virtual autopsy (virtopsy) is proposed, which uses minimally invasive radiology techniques such as postmortem CT scan (PM-CT) and PM-MRI. However, there is a scarcity of literature comprehensively summarizing this topic. Therefore, this review article discusses the advantages and limitations of virtopsy in developing countries during the COVID-19 pandemic, along with ethical issues and a proposed algorithm for postmortem imaging. Virtopsy improves the sensitivity (93%) and specificity (83%) of diagnoses and offers several advantages, such as faster identification, good foreign body detection, three-dimensional reconstruction, and non-invasiveness. Limitations include difficulty in determining infection status and assessing internal organ characteristics, operator dependence, insufficient legal basis, and high costs. During the COVID-19 pandemic, this article compiles twenty-one studies from 2020 to 2022 that used virtopsy to investigate 191 cases of COVID-19 infection resulting in death. The studies were conducted in various countries, with only two developing countries [Brazil (n = 3) and India (n = 1)] reported to have used it. Most of the studies used PM-CT, while others used postmortem ultrasound, PM-MRI, and PM chest X-ray. Virtopsies were mostly performed within 24 hours. The age range of the deceased individuals investigated using virtopsy was between 11 and 99 years old, with males being predominant. Virtopsy was mostly used for triage or screening for conventional autopsy (CA) as well as adjuvant/complement to CA. In summary, virtopsy has potential benefits for developing countries during and after the COVID-19 pandemic, making it a valuable investment despite its limitations.

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Fetal Autopsy Study Over a Two Year Period

Cited by 2 publications

References 6 publications

Evaluation of role of umbilical cord anomalies in fetal death-An institutional experience

Evaluation of role of umbilical cord anomalies in fetal death-An institutional experience

Virtopsy as a Breakthrough in Non-Invasive Autopsy: Its Principles and Potential of Application in Developing Countries During the Covid-19 Pandemic

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