Fertility preservation for social indications: a cost-based decision analysis

Clinical Value in IVF: Cycle Characteristics Associated With Gonadotropin Dose Change in IVF Patients Using Low Responder Protocols

“…Not included in this modeling is the cost of failed cycles using the new system, if it proves suboptimal. At a cost of approximately $10,000 per IVF cycle, a small number of failed cycles would quickly off-set the cost-savings of a more efficient stimulation protocol [12]. Prospective monitoring would elucidate how these methods perform in their ability to reduce costs and maintain clinical outcomes.…”

“…Ninety-nine patients using the flare protocol had 760 ultrasounds in 146 cycles (5.2±0.9 ultrasounds/cycle [range: [3][4][5][6][7][8], average cycle duration: 11.3±1.8 days [8][9][10][11][12][13][14][15][16]). Figure 1 shows the distribution of ultrasounds performed in flare cycles and how monitoring relates to management change.…”

Recent Advances in Assisted Reproductive Technology

“…While this trend has added to the richness and productivity of the world's economy, it has also increased the rate of age related female subfertility and infertility [49]. While ART has improved the prospects of achieving fertility for sub/ infertile women in their late 30's and early 40's, there still exists a significant rate of failure to conceive for this population [49].…”

“…In a similar manner, the ability to preserve a woman's fertility potential at a young age through oocyte cryopreservation has monumental social implications. The "biological clock" that women face as they approach their late 30s and early 40s certainly influences career decisions and places disproportionate pressure on women, as compared to men, to begin childbearing at relatively young ages [49]. As oocyte cryopreservation technology continues to improve and become less costly, its widespread use for elective fertility preservation by large segments of the population seems likely.…”

Human Ovarian Tissue Cortex Surrounding Benign and Malignant Lesions

“…[17][18][19][20][21][22][23][24][25] To avoid this risk, ongoing research is focused on isolating follicles from cryopreserved tissues to be grown using in vitro culture systems. 26,27 In order to obtain the tissue for cryopreservation, a partial or total oophorectomy is required. It is currently unclear whether ovarian lesions, either benign or malignant, can adversely affect the surrounding cortex and follicles within this cortex, thus limiting the likelihood that this tissue could be used for further fertility preservation strategies.…”