Fertility preservation for patients with gynecologic malignancies: The Korean Society for Fertility Preservation clinical guidelines

Lee, Sanghoon; Kim, Seul Ki; Hwang, Kyu Ri; Kim, Tak; Kim, Seok Hyun

doi:10.5653/cerm.2017.44.4.175

Cited by 14 publications

(9 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Following continuous progestin-based therapy, endometrial sampling must be performed every 3–6 months. If a patient shows complete remission after 6 months, she may attempt a pregnancy while being carefully monitored in every 3–6 months, and undergo surgical staging surgery, including total hysterectomy and/or bilateral salpingo-oophorectomy, upon pregnancy completion [ 44 ].…”

Section: Options On Fertility Preservation In Womenmentioning

confidence: 99%

Ovarian tissue cryopreservation and transplantation in patients with cancer

Kim

Lee

et al. 2018

Obstet Gynecol Sci

Self Cite

View full text Add to dashboard Cite

Chemotherapy and radiotherapy improved survival rates of patients with cancer. However, they can cause ovarian failure and infertility in women of reproductive age. Infertility following cancer treatment is considered a major quality of life issue. Ovarian tissue cryopreservation and transplantation is an important option for fertility preservation in adult patients with cancer who need immediate chemotherapy or do not want to undergo ovarian stimulation. Ovarian tissue freezing is the only option for preserving the fertility of prepubertal patients with cancer. In a recent review, it was reported that frozen-thawed ovarian transplantation has lead to about 90 live births and the conception rate was about 30%. Endocrine function recovery was observed in 92.9% between 3.5 and 6.5 months after transplantation. Based on our review, ovarian tissue cryopreservation and transplantation may be carefully considered before cancer treatment in order to preserve fertility and endocrine function in young cancer survivors.

show abstract

Section: Options On Fertility Preservation In Womenmentioning

confidence: 99%

Ovarian tissue cryopreservation and transplantation in patients with cancer

Kim

Lee

et al. 2018

Obstet Gynecol Sci

Self Cite

View full text Add to dashboard Cite

show abstract

“…Oocyte cryopreservation was recently accepted as a standard method for fertility preservation and is used worldwide [8,9]. Both oocyte and embryo cryopreservation require ovarian stimulation for approximately 2 weeks, which may result in delayed cancer treatment and excessive levels of estrogen exposure during stimulation [10].…”

Section: Introductionmentioning

confidence: 99%

Comparison between Slow Freezing and Vitrification for Human Ovarian Tissue Cryopreservation and Xenotransplantation

Lee

Ryu

Kim

et al. 2019

IJMS

Self Cite

View full text Add to dashboard Cite

Two methods for the cryopreservation of human ovarian tissue were compared using a xenotransplantation model to establish a safe and effective cryopreservation method. Ovarian tissues were obtained from women who underwent benign ovarian surgery in the gynecology research unit of a university hospital. The tissues were transplanted into 112 ovariectomized female severe combined immunodeficient mice 4 weeks after slow freezing or vitrification cryopreservation. Tissues were retrieved 4 weeks later. Primordial follicular counts decreased after cryopreservation and xenotransplantation, and were significantly higher in the slow freezing group than in the vitrification group (p < 0.001). Immunohistochemistry and TUNEL assay showed that the Ki-67 and CD31 markers of follicular proliferation and angiogenesis were higher in the slow freezing group (p < 0.001 and p = 0.006, respectively) and DNA damage was greater in the vitrification group (p < 0.001). Western blotting showed that vitrification increased cellular apoptosis. Anti-Müllerian hormone expression was low in transplanted samples subjected to both cryopreservation techniques. Electron microscopy revealed primordial follicle deformation in the vitrification group. Slow freezing for ovarian tissue cryopreservation is superior to vitrification in terms of follicle survival and growth after xenotransplantation. These results will be useful for fertility preservation in female cancer patients.

show abstract

“…Within current guidelines, fertility counseling often refers to the consultation where threatened fertility is initially discussed, by a medical practitioner or reproductive specialist, or simply reports on counseling as the provision of information without reference to counselor expertise . Fertility counseling, as a fertility information consultation, sits in line with the internationally recommended best‐practice approach; for timely discussion and provision of information by a medical team.…”

Section: Fertility Counselingmentioning

confidence: 99%

The psychological importance of fertility preservation counseling and support for cancer patients

Logan

Anazodo

2019

Acta Obstet Gynecol Scand

View full text Add to dashboard Cite

Infertility associated with cancer can have significant psychological impacts for cancer patients and survivors, necessitating appropriate fertility‐related psychological support. This literature review details the psychological impact of infertility in cancer patients and survivors, and discusses fertility counseling as described in current international guidelines; as either the provision of fertility information or psychosocial support. Fertility counseling has a role in assisting with fertility treatment decision‐making, but also in supporting patients with the emotional distress associated with potential infertility at the time of cancer diagnosis, and infertility in survivorship. The necessity of psychological support for fertility patients is outlined, alongside recommendations for adolescent and young adult patients, and family members of cancer patients involved in fertility and oncological care. Moving forward, clear guidelines for fertility counseling of cancer patients in the context of fertility preservation may be beneficial, in removing ambiguity as to whom conducts counseling, what counseling involves, and what level of psychosocial support may be most effective in supporting cancer patients longitudinally.

show abstract

Fertility preservation for patients with gynecologic malignancies: The Korean Society for Fertility Preservation clinical guidelines

Cited by 14 publications

References 30 publications

Ovarian tissue cryopreservation and transplantation in patients with cancer

Ovarian tissue cryopreservation and transplantation in patients with cancer

Comparison between Slow Freezing and Vitrification for Human Ovarian Tissue Cryopreservation and Xenotransplantation

The psychological importance of fertility preservation counseling and support for cancer patients

Contact Info

Product

Resources

About