Fertility, pregnancy outcomes and deliveries following myomectomy: experience of a French Caribbean University Hospital

Abstract

The modest conception rate (43.5%) after myomectomy among those women trying to obtain a pregnancy may be linked to the specificities of our population, and in particular its relatively high age and the frequent association of multiple causes of infertility.

Systematic review of pregnancy outcomes after fertility-preserving treatment of uterine fibroids

“…These pregnancies resulted in 1191 live births (75.6%), 42 ongoing pregnancies (2.7%), 299 miscarriages (19.0%), 24 ectopic pregnancies (1.5%) and two stillbirths. Of the 17 pregnancies that were terminated (1.1%), three were caused by fetal anomaly, one was caused by chromosomal abnormalities, whereas the remaining terminations were for either social or maternal medical reasons (Dessolle et al, 2001;Soriano et al, 2003;Kumakiri et al, 2005;Paul et al, 2006;Seracchioli et al, 2006;Mara et al, 2008;Bernardi et al, 2014;Borja de Mozota et al, 2014;Sangha et al, 2015). A total of six placental abnormalities were reported (four placenta previa, one placenta accreta and one placenta percreta (Dubuisson et al, 2001;Paul et al, 2006;Tinelli et al, 2012;Pitter et al, 2013).…”

Time to conceive after myomectomy: should we advise a minimum time interval? A systematic review

“…Only 80 articles were considered eligible for this study, of which 43 articles met the primary objective of time interval between myomectomy and pregnancy. The 43 studies were from 15 different countries; 29 (67.4%) were retrospective studies (Bernardi et al, 2014;Borja de Mozota et al, 2014;Connolly et al, 2000;Dessolle et al, 2001;Fauconnier et al, 2000;Fukuda et al, 2013;Huberlant et al, 2020a;Kang et al, 2020;Kelly et al, 2008;Koo et al, 2015;Kumakiri et al, 2005Kumakiri et al, , 2008Lebovitz et al, 2019;Malzoni et al, 2010;Morita and Asakawa, 2006;Paul et al, 2006;Pepin et al, 2020;Pitter et al, 2015Pitter et al, , 2013Pundir et al, 2015;Rovio and Heinonen, 2012;Seinera et al, 2000;Seracchioli et al, 2006;Soriano et al, 2003;Tian et al, 2015;Tsuji et al, 2016;Tusheva et al, 2013;Yoshino et al, 2012;Zhang and Hua, 2014), nine (20.9%) were prospective or cohort studies (Cela et al, 2013;Chang et al, 2009;Chen et al, 2017;Lönnerfors andPersson, 2009, 2011;Nishida et al, 2014;Plotti et al, 2008;Tinelli et al, 2012;Wu et al, 2020), and five (11.6%) were prospective randomized studies (Kameda et al, 2018;Kim et a...…”

Improved Fertility Following Enucleation of Intramural Myomas in Infertile Women

“…Furthermore, Borja de Mozota et al . [15] conducted a study including 297 infertile women with myomas, and demonstrated that age (over 35 years, RR = 2.450) was a negative factor for fertility.…”