Fertility and pregnancy outcome among women undergoing assisted reproductive technology treatment in Windhoek, Namibia

Lucas, Adão Francisco; Gemechu, Dibaba B; Plessis, Stefan S. du; Aboua, Yapo Guillaume

doi:10.1007/s10815-020-02046-4

Cited by 5 publications

(4 citation statements)

References 37 publications

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“…Assisted reproduction technologies (ART) include ovulation induction, IVF, and subsequent embryo transfer to the uterus, and treatment with exogenous human chorionic gonadotropin or progesterone [9] .…”

Section: Highlightsmentioning

confidence: 99%

The prevalence of antiphospholipid antibodies and effects on the outcomes of in vitro fertilization

Halki,

Khalayli,

Haidar

et al. 2024

International Journal of Surgery: Global Health

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Introduction: The problem of infertility is common worldwide. IVF remains the most widely used technique of assisted reproductive technology. Embryo implantation failure is a common cause of unexplained infertility and recurrent miscarriages, thus the relationship between antiphospholipid antibodies and embryo implantation failure after IVF and embryo transfer is an important problem in fertility medicine that must be studied. Patients and methods: A retrospective and prospective (bidirectional) cohort study were conducted at the Laboratory Department of the Faculty of Medicine, and Hospital from June 2017 to June 2021. The sample size was 1000 participants, 900 of them were retrospective (2017–2020), and 100 were prospective (2020–2021). Data was collected, including patients’ demographics, type and duration of fertility, and antiphospholipid antibody values. Inclusion criteria-Women <40 years old, undergoing IVF, and in the retrospective study, patients who undergo IVF and who have antibody data, positivity of phospholipids, and/or anticardiolipin, and/or B2 glycoprotein I, and the presence of the gestational sac on ultrasound as a criterion for pregnancy. We performed a PTT LA for the control group in a cohort study (20 healthy women), then a PTT LA test, and the blending test were performed, and the values were considered positive if the correction was not made. The PTT LA test is a screening test. Results: The average age of the women was 31.91, the success rate of assisted fertilization in inducing pregnancy in the last trial was 52.8%, the prevalence was 4.4% of anticardiolipin IgG, 2.6% of anticardiolipin IgM, and 4% of Lupus anticoagulant. No relation was found between the antiphospholipid value and the age of the women, the number of times the experiment was conducted, the rate of success and failure, the type of infertility, and the number of oocytes induction, while the duration of sterility was affected by positive values of IgG and lupus coagulant antibodies. Conclusion: There is no need for a routine antiphospholipid assay for female candidates for IVF, and when it is confirmed, treatment is required by Anticoagulants.

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Section: Highlightsmentioning

confidence: 99%

The prevalence of antiphospholipid antibodies and effects on the outcomes of in vitro fertilization

Halki,

Khalayli,

Haidar

et al. 2024

International Journal of Surgery: Global Health

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“…Mitochondrial activity in sperm is improved by Myo-Ins, which has a positive impact on a wide variety of sperm processes [239], including capacitation, acrosome response, and motility regulation. This results in an increase in the motility of sperm in patients who already have aberrant sperm parameters [240]. In this regard, Governini et al [241] demonstrated that sperm motility is noticeably enhanced following treatment with myo-Ins.…”

Section: Inositolsmentioning

confidence: 99%

Role of Antioxidants of Natural Herbs in Management of Male Infertility

Gaznee¹,

Kohli²,

Kumar³

2023

J. Res. Appl. Sci. Biotechnol.

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If you and your spouse have been trying to conceive for a year and neither of you has been successful, there is a possibility that you are one of the 50–80 million people throughout the world who struggle with infertility. There is a male component present in approximately 20%-30% of these instances. It is common knowledge that low-quality sperm and oxidative stress (OS) both have a role in the aetiology of male infertility. Because of the oxidation of DNA, proteins, and lipids, excessive levels of reactive oxygen species (ROS) have the potential to disrupt the viability, motility, and morphology of sperm cells. ROS are responsible for these changes. Methods: Through the use of the PubMed interface, we searched the MEDLINE database for studies that had been completed and published during the past ten years that analysed the effect that antioxidants had on sperm in infertile guys (2012–2022). A number of different phrases, including infertility, alpha-lipoic acid, zinc, folate, coenzyme Q10, selenium, and vitamin, were utilised during the search. The study's findings indicate that inositol serves a purpose in a number of different mechanisms that foster contacts between sperm and oocytes, and that it also affects OS levels in sperm cells by way of its engagement in mitochondrial events. Alpha-lipoic acid (ALA) lessens the damage caused by reactive oxygen species (ROS) and improves the quality of sperm in a number of ways, including motility, morphology, and count. There might be a connection between not getting enough zinc in your diet and having low-quality sperm. Zinc and folate are two nutrients that can boost the quantity and quality of sperm. When taken orally, coenzyme Q10 increases the number of sperm as well as their overall motility and forward movement. A therapy with selenium (Se) results in an improvement in the sperm's overall quality, and this improvement is connected with an increase in ejaculatory production. Only vitamin B12 has been found to improve the quality of sperm; it does this by boosting sperm count and motility and by decreasing sperm DNA damage. Vitamin B12 is the only vitamin that has been proved to do this. Conclusions: Dietary supplementation with antioxidants may improve sperm quality in men with low-quality semen by reducing OS-induced sperm damage and increasing hormone synthesis and spermatozoa concentration, motility, and morphology. This may be achieved in men who also have low levels of antioxidants in their semen. Antioxidants can exert their effects in a variety of ways; hence, it is important for researchers conducting future clinical trials to study the possibility of combining a number of antioxidants.

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“…In last few decades, it has been observed that couple avoids having parenthood before 35 years. Such delaying in family planning may affect female fertility [46][47][48][49] . If a couple not able to have a child even after having unprotected sex for more than a year should visit a medical center.…”

Section: Fertility Problemsmentioning

confidence: 99%

Role of Nurses in the Management of Common Gynecological Diseases: Recent Advances

Tuli

2021

JCNR

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In recent years the role of the specialist nurse with respect to gynecology and women’s health has gained significant importance. The advancement in the nursing practice has provided an insight to interact with patients to explore their history. Such hysteroscopy procedures may not only give a better feel to the patient but also explore the need for doctor treatment. The review updates about the ongoing advances in the field of nursing science to upgrade the life of patients with gynecological diseases. Evidence has suggested the promising role of nurses to motivate patients with improved health after the treatment. The present review will cover the various health issues of women including menstrual dysfunction, fertility, and management of pregnancy’s termination, uro-gynecological issues, and gyne-oncology, etc. The role of nurses during the above health issue will be discussed via various procedures. Therefore, the present review will conclude the significant importance of nurses in women’s health issues to sustain happiness and to strengthen the need to bring advances in the curriculum of nurses to full fill the requirement of medical staff.

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Fertility and pregnancy outcome among women undergoing assisted reproductive technology treatment in Windhoek, Namibia

Cited by 5 publications

References 37 publications

The prevalence of antiphospholipid antibodies and effects on the outcomes of in vitro fertilization

The prevalence of antiphospholipid antibodies and effects on the outcomes of in vitro fertilization

Role of Antioxidants of Natural Herbs in Management of Male Infertility

Role of Nurses in the Management of Common Gynecological Diseases: Recent Advances

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