Fertility after implementation of long- and short-term progesterone-based ovulation synchronization protocols for fixed-time artificial insemination in beef heifers

Kasimanickam, R.; Schroeder, Stephen R.; Hall, J. B.; Whittier, W. Dee

doi:10.1016/j.theriogenology.2015.01.004

Cited by 13 publications

(6 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The overall mean time interval between intravaginal device removal and the beginning of estrus (42.6 h) was similar to the range (42-45 h) reported by Peralta-Torres et al (2010b) but was smaller than the mean (49.3 h) reported by Colazo et al (2003). Time from intravaginal device removal to estrus is important for establishing the best moment for FTAI (Ayres et al, 2008;Kasimanickam et al, 2015). Ovulation occurs 30 and 31 h after cows estrous manifestation when EC or EB is used (Peralta-Torres et al, 2010a).…”

Section: Discussionsupporting

confidence: 82%

“…These latter authors reported a higher pregnancy rate after FTAI in heifers with a mature reproductive tract (grades 5 and 4 with 80% and 70%, respectability) compared to heifers with an immature reproductive tract (grades 3, 2, and 1 with 53%, 40%, and 31%, respectability) (P<0.05). Kasimanickam et al (2015) also reported an increased pregnancy rate in heifers with more mature RTD. However, Cutaia et al (2006), Stevenson et al (2008), and Butler et al 2011did not find an association (P>0.05) between stage of uterus development and pregnancy rate in heifers.…”

Section: Discussionmentioning

confidence: 88%

See 1 more Smart Citation

Effects of reproductive tract development and hormonal treatment on estrous synchronization in heifers

et al. 2020

View full text Add to dashboard Cite

Evaluation of the reproductive tract development (RTD) is a criterion rarely used when heifers are included in estrous synchronization programs. The objective of the present study was to determine the effect of RTD (mature and immature) and hormonal treatment (EC and EB) on estrous expression rate and pregnancy rate in Bos indicus heifers under tropical conditions. RTD was evaluated with an ultrasound and classified as mature (n=99) or immature (n=101). Heifers received an intravaginal device (DIB®; day 0), 2 mg of estradiol benzoate (EB) and 250 µg of cloprostenol (PGF2α). The DIB was removed on day 7 post insertion, and 250 µg of PGF2α was applied and heifers were divided into two groups: One group of heifers received 0.5 mg of estradiol cypionate (EC group), and on day 8, a second group of heifers received 1 mg of estradiol benzoate (EB group). Estrus was detected by visual observation, and all heifers were inseminated at a fixed-time (FTAI). Fifteen days after insemination, bulls were introduced to the treatment groups. Data were analyzed using general modeling and binary logistic regression procedures. The percentage of estrus was similar for both mature and immature heifers (P>0.05), however, the heifers treated with EB had 17% animals in estrus, than the heifers that received EC (P <0.05). The pregnancy rate after FTAI (74.8%) and total pregnancy (FTAI + natural mating = 91.9%) was greater for the group of heifers with a mature reproductive tract (P<0.05). The hormone treatment had not effect (P>0.05) on the pregnancy rate. In conclusion, the heifers with mature reproductive tracts had the highest pregnancy rate after artificial insemination and total pregnancy. Hormonal treatment did not influence the pregnancy rate.

show abstract

Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 88%

Effects of reproductive tract development and hormonal treatment on estrous synchronization in heifers

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Further, exclusion of GnRH treatment resulted in a tight synchrony of oestrus and showed a similar tendency to improve FTAI pregnancy rates compared to when GnRH was administered (Atkins et al., ; Mallory et al., ). Two experiments in a previous study, this 14‐day approach without GnRH on day 23 resulted in acceptable FTAI pregnancy rates (54.5% and 56.9%) (Kasimanickam et al., ). In the present study, the AI‐PR for heifers in No‐GnRH72 was 62.8%, whereas AI‐PR for heifers in GnRH72 groups was 60.9%.…”

Section: Discussionmentioning

confidence: 97%

“…Irrespective of expression of oestrus, these protocols are designed to induce the ovulation of a mature‐dominant follicle containing a competent ovum in all treated females. Previous studies using 5‐day, 7‐day and 14‐day controlled internal drug release (CIDR) protocol reported varying pregnancy rates following AI (Bridges et al., ; Kasimanickam, Asay, Firth, Whittier, & Hall, ; Kasimanickam, Schroeder, Hall, & Whittier, ; Mallory, Nash, Ellersieck, Smith, & Patterson, ). To promote extensive adoption of these protocols, pregnancy rates following FTAI should be similar to protocols utilizing oestrous detection and AI and be consistent across groups of heifers (Lamb et al., ).…”

Section: Introductionmentioning

confidence: 99%

Fertility of Angus cross beef heifers after GnRH treatment on day 23 and timing of insemination in 14‐day CIDR protocol

Kasimanickam

Hall

Whittier

2016

Reprod Domestic Animals

View full text Add to dashboard Cite

This study compared artificial insemination pregnancy rate (AI-PR) between 14-day CIDR-GnRH-PGF2α-GnRH and CIDR-PGF2α-GnRH synchronization protocol with two fixed AI times (56 or 72 hr after PGF2α). On day 0, heifers (n = 1311) from nine locations assigned body condition score (BCS: 1, emaciated; 9, obese), reproductive tract score (RTS: 1, immature, acyclic; 5, mature, cyclic) and temperament score (0, calm; and 1, excited) and fitted with a controlled internal drug release (CIDR, 1.38 g of progesterone) insert for 14 days. Within herd, heifers were randomly assigned either to no-GnRH group (n = 635) or to GnRH group (n = 676), and heifers in GnRH group received 100 μg of GnRH (gonadorelin hydrochloride, IM) on day 23. All heifers received 25 mg of PGF2α (dinoprost, IM) on day 30 and oestrous detection aids at the same time. Heifers were observed for oestrus thrice daily until AI. Within GnRH groups, heifers were randomly assigned to either AI-56 or AI-72 groups. Heifers in AI-56 group (n = 667) were inseminated at 56 hr (day 32 PM), and heifers in AI-72 group (n = 644) were inseminated at 72 hr (day 33 AM) after PGF2α administration. All heifers were given 100 μg of GnRH concurrently at the time AI. Controlling for BCS (p < .05), RTS (p < .05), oestrous expression (p < .001), temperament (p < .001) and GnRH treatment by time of insemination (p < .001), the AI-PR differed between GnRH treatment [GnRH (Yes - 60.9% (412/676) vs. No - 55.1% (350/635); p < .05)] and insemination time [AI-56 - 54.6% (364/667) vs. AI-72 - 61.8% (398/644); (p < .01)] groups. The GnRH treatment by AI time interaction influenced AI-PR (GnRH56 - 61.0% (208/341); GnRH72 - 60.9% (204/335); No-GnRH56 - 47.9% (156/326); No-GnRH72 - 62.8% (194/309); p < .001). In conclusion, 14-day CIDR synchronization protocol for FTAI required inclusion of GnRH on day 23 if inseminations were to be performed at 56 hr after PGF2α in order to achieve greater AI-PR.

show abstract

“…The present study has shown a better conception rate than reports in crossbred cattle (40.9%) in the tropics [3], in Holstein Friesian/crossbred cows (45.5%) [28], in Bos indicus cattle [15] and in beef cattle in USA [12], and in beef heifers (54.5/55.5%) using 14-day/ 5-dayCIDR protocols [49] that reported lower pregnancy rates, 54.5% and 55.5%, when used long and short term CIDR protocols, respectively. Moreover, the present study has shown better conception rate in repeat breeder cows/heifers than previous reports in South Korea [26] and Japan [33].…”

Section: Discussionmentioning

confidence: 40%

Manipulation of Fertility in Crossbred Dairy Cattle Using Controlled Internal Drug Release Device Combined With Prostaglandin and Equine Chorionic Gonadotrophin

Mekonnin

Howie

Harlow³

et al. 2016

AVS

View full text Add to dashboard Cite

Abstract:Simplifying and improving our understanding of the protocols for inducing or synchronizing estrus is important for improving management of dairy cattle. This study evaluated the estrus response and conception rate of crossbred (Holstein Friesian X Zebu) dairy cows (n=75) and heifers (n=47) assigned to a 10-day controlled internal drug release (CIDR) deviceprostaglandin F2-alpha (PGF2α) -equine chorionic gonadotrophin (eCG) based estrus synchronization protocol. Animals were assigned to three groups (a) anestrus (n=62), (b) repeat-breeders (n=11) and (c) silent estrus (n=46), according to their reproductive history, per rectal palpation, and progesterone concentrations determined by On-Farm enzyme-linked immunosorbent assays (ELISA) in milk (lactating cows) or serum (dry cows and heifers). For each animal, a CIDR device (containing 1.38g progesterone) was inserted into the vagina and allowed to remain in-situ for 10 days. On Day 8 after device insertion, a dose of 500µg of PGF2α was administered intramuscularly (IM). On Day 10 (device removal), 500 IU of eCG was given IM. Animals were inseminated or mated 48 and 72 hrs post device removal. Pregnancy was assessed 20-24 days post insemination by measurement of progesterone in milk/serum and pregnancy was confirmed by per rectal palpation and/or ultrasonography 44-90 days post insemination. Overall estrus response and conception rates were 97.5% and 78.3%, respectively, with no significant differences in parity, pre-treatment reproductive status and farming system (smallholder vs organized commercial farms). Conception rate after induced/synchronized estrus was 82.9% and 72.1% in cows and heifers, respectively, with an overall calving rate of 94.4%. In conclusion, the present study has shown high estrus response and conception rate in crossbred dairy cattle using this CIDR -PGF2α -eCG based estrus synchronization protocol. Application of this protocol is highly recommended to enhance fertility of dairy cattle in the study area, and this could readily be applied to other regions.

show abstract

Fertility after implementation of long- and short-term progesterone-based ovulation synchronization protocols for fixed-time artificial insemination in beef heifers

Cited by 13 publications

References 34 publications

Effects of reproductive tract development and hormonal treatment on estrous synchronization in heifers

Effects of reproductive tract development and hormonal treatment on estrous synchronization in heifers

Fertility of Angus cross beef heifers after GnRH treatment on day 23 and timing of insemination in 14‐day CIDR protocol

Manipulation of Fertility in Crossbred Dairy Cattle Using Controlled Internal Drug Release Device Combined With Prostaglandin and Equine Chorionic Gonadotrophin

Contact Info

Product

Resources

About