Fertility after Correction of Bilateral Undescended Testes at the Age of 23 Years

Traumatic bilateral testicular dislocation: a recovery of spermatogenesis by orchiopexy 15 years after the onset

“…Moreover, Pollen and Funckes showed a recovery of the spermatogenetic function after the repair of a dislocation by a semen analysis in a man with an absence of active spermatogenesis (7). In contrast, the histologic changes of the testes deteriorate with age in the cryptorchid testes (11)(12)(13)(14). Raman and Schlegel showed age at orchiopexy to be an independent predictor of successful sperm retrieval for men with persistent azoospermia with a history of cryptorchidism (11).…”

“…The cryptorchid testis may have an inherently normal composition that is adversely affected by the local environment and that is dependent on time (11)(12)(13)(14). Furthermore, men with bilateral cryptorchidism who underwent corrective surgery after puberty had a very poor chance of fertility (11)(12)(13)(14). Histologic change also may progress to an irreversible state as tubular atrophy with prominent interstitial cells, tubular wall thickness seen in adult cryptorchid testis, if the dislocated testis remains untreated for long periods of time.…”

“…Raman and Schlegel showed age at orchiopexy to be an independent predictor of successful sperm retrieval for men with persistent azoospermia with a history of cryptorchidism (11). The cryptorchid testis may have an inherently normal composition that is adversely affected by the local environment and that is dependent on time (11)(12)(13)(14). Furthermore, men with bilateral cryptorchidism who underwent corrective surgery after puberty had a very poor chance of fertility (11)(12)(13)(14).…”

The relationship of cryptorchidism to fertility

“…For example, there is a report of a man with testes of normal volume that were located in the superficial inguinal ring until correction when he was 23 years of age who subsequently fathered four children [43]. Although reported, this is clearly an exception to the norm; nearly all clinicians would suggest that infertility would result among patients with untreated bilateral cryptorchidism.…”

Maldescended Testis: causes and treatments

“…En s'appuyant sur un cas similaire rapport6 quelques ann6es auparavant [29], et sur le cas unique qu'ils rapportaient [61] les auteurs concluaient leur article en " recommandant de r6aliser une orchidopexie chez les hommes adultes avec des TND palpables consultant pour inf6condit4, sans tenir compte des r4sultats des analyses de sperme ou des taux de FSH ". Bien que cet article ait 6t4 publi6 dans une respectable revue, on peut penser que le "reviewer" air 6t6 quelque peu somnolent devant une conclusion aussi largement document4e !…”