Ferroptosis in Glaucoma: A Promising Avenue for Therapy
Jingyun Zhu,
Hui Chen,
Jian Wu
et al.
Abstract:Glaucoma, a blind‐leading disease largely since chronic pathological intraocular high pressure (ph‐IOP). Hitherto, it is reckoned incurable for irreversible neural damage and challenges in managing IOP. Thus, it is significant to develop neuroprotective strategies. Ferroptosis, initially identified as an iron‐dependent regulated death that triggers Fenton reactions and culminates in lipid peroxidation (LPO), has emerged as a focal point in multiple tumors and neurodegenerative diseases. Researches show that ir… Show more
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