Ferroptosis and cuproptosis: Metal-dependent cell death pathways activated in response to classical chemotherapy – Significance for cancer treatment?

Kciuk, M.; Gielecińska, A.; Kałuzińska-Kołat, Ż.; Yahya, E.B.; Kontek, R.

doi:10.1016/j.bbcan.2024.189124

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

2024

DOI: 10.1016/j.bbcan.2024.189124

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Ferroptosis and cuproptosis: Metal-dependent cell death pathways activated in response to classical chemotherapy – Significance for cancer treatment?

M. Kciuk,

A. Gielecińska,

Ż. Kałuzińska-Kołat

et al.

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2024

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Cited by 2 publications

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Targeting cuproptosis for cancer therapy: Focus on the anti-tumor immune system

Zhang,

Han

2024

Cancer Pathogenesis and Therapy

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Targeting cuproptosis for cancer therapy: Focus on the anti-tumor immune system

Zhang,

Han

2024

Cancer Pathogenesis and Therapy

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Copper ions: The invisible killer of cardiovascular disease (Review)

Wang,

Feng,

et al. 2024

Mol Med Rep

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Copper, a vital trace element, is indispensable for the maintenance of physiological functioning, particularly in the cardiac system. Unlike other forms of cell death such as iron death and apoptosis, copper-induced cell death has gained increasing recognition as a significant process influencing the development of cardiovascular diseases. The present review highlights the significance of maintaining copper homeostasis in addressing cardiovascular diseases. This review delves into the crucial roles of copper in physiology, including the metabolic pathways and its absorption, transport and excretion. It provides detailed insights into the mechanisms underlying cardiovascular diseases resulting from both excess and deficient copper levels. Additionally, it summarizes strategies for treating copper imbalances through approaches such as copper chelators and ion carriers while discussing their limitations and future prospects.

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Ferroptosis and cuproptosis: Metal-dependent cell death pathways activated in response to classical chemotherapy – Significance for cancer treatment?

Cited by 2 publications

References 189 publications

Targeting cuproptosis for cancer therapy: Focus on the anti-tumor immune system

Targeting cuproptosis for cancer therapy: Focus on the anti-tumor immune system

Copper ions: The invisible killer of cardiovascular disease (Review)

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