Ferrocenoyl-amino acids: redox response towards di- and trivalent metal ions

Mercury binding by ferrocenoyl peptides with sulfur-containing side chains: Electrochemical, spectroscopic and structural studies

“…of Hg(II) changes by 69 mV from the redox potential of the free peptide; the other four compounds exhibit potential changes of between 31 and 47 mV in response to Hg(II). These changes are modest, but are comparable to shifts exhibited by other cationbinding ferrocenoyl peptide systems [17,23]. Each mercury response curve shows a similar plateau effect, with potential changes halting abruptly once between one and 2 equiv.…”

“…Ferrocene derivatives have been extensively utilised to study the interactions of chemical hosts with metal ions and other substrates, exploiting the electrochemical properties of the Fe(II)/ Fe(III) redox couple [14][15][16][17][18]. The highly reproducible redox behaviour of the ferrocene/ferrocenium redox system enables a range of electrochemical methods, with cyclic voltammetry (CV) most commonly employed [14,16].…”

“…However the use of ferrocenoyl peptides in cation sensing applications has received comparatively little attention to date. Kraatz et al recently utilised ferrocene-containing bioconjugates for the selective detection of various cations including Li(I), K(I), Cs(I), Mg(II) and La(III) [23,17], and in a related study Cheng et al have prepared a family of ferrocene-linked cyclopseudopeptides and examined their binding properties to alkaline earth metals [24].…”

Synthesis, electrochemistry and metal binding properties of monosubstituted ferrocenoyl peptides with thioether-containing sidechains

“…However the potential of ferrocenoyl peptides for cation sensing applications has received comparatively little attention to date. Kraatz and coworkers have utilised ferrocenecontaining bioconjugates for the selective detection of various cations including lithium(I), potassium(I), cesium(I), magnesium (II) and lanthanum(III) [23,48], and in a related study the Cheng group have prepared a family of ferrocene-linked cyclopseudopeptides and examined their capacity to bind alkaline earth metals [49].…”

N-acylbenzotriazole mediated microwave assisted synthesis of protected and novel unprotected ferrocenoylamidoamino acids

“…Ferrocene amino acids [3,4,5,6,7,8,9,10,11,12] and peptides [13,14,15,16,17] have been widely prepared and used in different applications such as binding or caging structures for metal ions [18]. In previous preparation procedures, ferrocenoyl halides (i.e.…”