Fermentation of lignocellulosic hydrolysates. I: inhibition and detoxification

“…Alkaline compounds which commonly used are Ca(OH) 2 and NH 4 OH. The addition of alkali can reduce furan and HMF found in hydrolysates, resulting in increased productivity of ethanol from fermentation [8].…”

Section: Introductionmentioning

confidence: 99%

Bioethanol Production from Seaweed Eucheuma cottonii by Neutralization and Detoxification of Acidic Catalyzed Hydrolysate

Fakhrudin¹,

Setyaningsih²,

Rahayuningsih³

2014

IJESD

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“…1, 3, and 4). Efficient detoxification methods are therefore required to improve the utility of lignocellulosic hydrolysate as a fermentation feedstock (1,5,6).…”

mentioning

confidence: 99%

Identification and characterization of the furfural and 5-(hydroxymethyl)furfural degradation pathways of Cupriavidus basilensis HMF14

Koopman

Wierckx

Winde

et al. 2010

Proc. Natl. Acad. Sci. U.S.A.

221

240

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The toxic fermentation inhibitors in lignocellulosic hydrolysates pose significant problems for the production of second-generation biofuels and biochemicals. Among these inhibitors, 5-(hydroxymethyl)furfural (HMF) and furfural are specifically notorious. In this study, we describe the complete molecular identification and characterization of the pathway by which Cupriavidus basilensis HMF14 metabolizes HMF and furfural. The identification of this pathway enabled the construction of an HMF and furfural-metabolizing Pseudomonas putida. The genetic information obtained furthermore enabled us to predict the HMF and furfural degrading capabilities of sequenced bacterial species that had not previously been connected to furanic aldehyde metabolism. These results pave the way for in situ detoxification of lignocellulosic hydrolysates, which is a major step toward improved efficiency of utilization of lignocellulosic feedstock.

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Fermentation of lignocellulosic hydrolysates. I: inhibition and detoxification

Cited by 1,201 publications

References 43 publications

Lignocellulose biodegradation: Fundamentals and applications

Lignocellulose biodegradation: Fundamentals and applications

Bioethanol Production from Seaweed Eucheuma cottonii by Neutralization and Detoxification of Acidic Catalyzed Hydrolysate

Identification and characterization of the furfural and 5-(hydroxymethyl)furfural degradation pathways of Cupriavidus basilensis HMF14

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