Fermentation of dried distillers’ grains and solubles (DDGS) hydrolysates to solvents and value-added products by solventogenic clostridia

Biological activities of lignin hydrolysate-related compounds

“…Considering it is not a foodstuff, it is regarded an essential material source for environmental friendly fuels (2). Moreover, the production of bioethanol or biobutanol using different types of lignocellulosic biomass has been tested by several groups, with the research results showing plant biomass-derived cellulose to be potential and feasible source of sugars (3)(4)(5). Lignocellulose, as a chemical, is a complex biopolymer composed of mainly three parts: cellulose, hemicellulose and lignin (6).…”

“…These components can be generally classified based on their structure and include weak acids, furan derivatives and phenolic compounds (9,10). These compounds have been found to be toxic to the microbes employed to ferment the sugars and produce the useful solvents (5,11). For instance, phenolics, such as p-coumaric acid and ferulic acid, showed inhibitory effects on the production ABE by clostridial strains, while in tests with E. coli, phenolic compounds and furan derivatives, such as furfural and HMF, inhibited the cell growth and fermentation (12,13).…”

Production of Biofuels from Cellulose of Woody Biomass

“…Similar to ethanol production, the enzymatic hydrolysis of polysaccharides to monosaccharides and then fermentation to biosolvents were carried out in the past [78]. The drawbacks of this process is its energy intensity, which makes its commercialization costly [78,79].…”

Design of Sustainable Supply Chains for the Agrifood Sector: A Holistic Research Framework

“…However, a major challenge hampering re-commercialization of the ABE process is lack of economic competitiveness, stemming in part from the absence of inexpensive, readily available, and easily fermentable substrates capable of generating high ABE yields (Qureshi and Blaschek 2000;Yu et al 2007). Interestingly, solventogenic Clostridium species are capable of fermenting a wide range of carbohydrates (Ezeji and Blaschek 2008), and lignocellulosic biomass has been identified as a potential substrate for inexpensive production of ABE and other fine chemicals (Ezeji and Blaschek 2008;Zhang and Ezeji 2013). However, bioconversion of lignocellulosic biomass is currently plagued by a number of limitations, notably generation of microbial inhibitory compounds during pretreatment and hydrolysis of lignocellulose to mixed sugars (Almeida et al 2007), and inefficient utilization of the generated mixed sugars by fermenting microorganisms due to carbon catabolite repression (Ren et al 2010).…”