Fenugreek (Trigonella foenum-graecumL. Leguminosae): An Evidence-Based Systematic Review by the Natural Standard Research Collaboration

Abstract

An evidence-based systematic review including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology and dosing.

Adverse effects of herbal medicines: an overview of systematic reviews

“…26 Thirty-one SRs concluded that the HM in question was safe. [13][14][15][16][17][18][19][20][21][23][24][25][26]29,31,32,35,38,39,[42][43][44][45]47,50,53,55,[57][58][59][60] Fifteen SRs reported moderately severe AEs, 12,22,27,28,30,36,40,41,46,48,49,51,52,54,56 and four SRs concluded that the HM in question was not safe (see Supplemental Tables S1 and S2). 33,34,37,…”

“…Forty-two SRs failed to mention conflict of interest of the authors. [13][14][15][16][17][18]22,23,[25][26][27][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61] Thirty-two SRs made no mention of any source of funding. [13][14][15][16][17]22,23,27,30,[34]…”

“…Some SRs also included secondary analyses such as review articles. 15,23,45,47,51,52,59,61 One SR employed a meta-analytical approach. 26 Thirty-one SRs concluded that the HM in question was safe.…”

“…[13][14][15][16][17]21,23,27,[32][33][34][35][36][37][38][39][40]45,47,[50][51][52][53][54][55][56][57][58][59][60][61] The number of primary studies included in the SRs ranged from 1 38 to 216. 28 The types of primary reports varied from case studies to epidemiological investigations.…”

Acute Toxicity Evaluation of Protodioscin Rich Extract of Trigonella Foenum-Graecum L in Rats

“…In India, it is commonly consumed as a condiment. It is used in indigestion, arthritis, spondylosis, baldness, diabetes mellitus, and hyperlipidemia [3][4][5][6]. It is also used as appetizer and galactogogues [2,7].…”