Fenolik Bileşiklerin Bağlı Formları ve Biyoyararlılığı

Karabulut, Gulsah; Yemiş, Oktay

doi:10.24323/akademik-gida.667270

Cited by 16 publications

(5 citation statements)

References 91 publications

(86 reference statements)

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“…The phenolic compounds performance play an important role in retaining the balance between oxidants and antioxidants in the body. Studies have shown that dietary intake of phenolic compounds associated with oxidative stress can prevent diseases such as cancer, high cholesterol, coronary heart, cataracts, diabetes, cardiovascular diseases, and aging (Karabulut & Yemiş, 2019). Total phenolic and flavonoid contents of G. biloba leaf methanol extract were measured as 71.20±0.42 µg GAE/mg extract and 13.24±0.35 µg QE/mg extract, respectively.…”

Section: Discussionmentioning

confidence: 99%

Gingko biloba L.’nın Fitokimyasal Bileşimi, Antioksidan ve Anti-Kanser Aktiviteleri Üzerine Bir Araştırma

YILMAZ,

DEVECİ,

TEL-ÇAYAN

2023

Comm. J. Biol.

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The study aims to investigate the phytochemical composition, antioxidant potential, and anti-cancer activities of Ginkgo biloba L. leaf methanol extract. In this study, the phytochemical compounds, total phenolic and flavonoid contents of G. biloba leaf methanol extract were investigated. Additionally, antioxidant and anti-cancer activities [against HT-29 (human colon cancer line), HeLa (human cervical cancer line), and HEK-293 (human embryonic kidney cell line)] were assayed. The main phytochemical compounds were identified as gallic (0.94±0.01 mg/g), p-hydroxy benzoic (0.71±0.01 mg/g), and protocatechuic (0.60±0.02 mg/g) acids in G. biloba leaf methanol extract by HPLC. The total phenolic and total flavonoid contents were measured as 71.20±0.42 µg GAE/mg extract and 13.24±0.35 µg QE/mg extract, respectively. The high antioxidant activity was found in ABTS•+ assay (89.04±0.71%) while moderate antioxidant activity was observed in DPPH• (43.31±0.75%), metal chelating (49.04±0.49%), CUPRAC (absorbance: 0.85±0.01), and phosphomolybdenum (absorbance: 1.16±0.02) assays at 400 µg/mL. The IC50 values of G. biloba leaf methanol extract on HT-29, HeLa, and HEK-293 cell lines were recorded as 406.70±1.55, 84.86±0.98, and >800 µg/mL, respectively. The present study features a new addition to the antioxidant and anti-cancer properties of the therapeutically valuable G. biloba with its phytochemical content.

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Section: Discussionmentioning

confidence: 99%

Gingko biloba L.’nın Fitokimyasal Bileşimi, Antioksidan ve Anti-Kanser Aktiviteleri Üzerine Bir Araştırma

YILMAZ,

DEVECİ,

TEL-ÇAYAN

2023

Comm. J. Biol.

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“…It is known that sprouts have more antioxidant content than seeds. In another study, it was mentioned that kumestrol, obtained from soybean sprouts, suppresses prostate cancer (Karabulut and Yemiş, 2019;Kalaycı and Kaya, 2022) High blood pressure or hypertension, which is a symptom of cardiovascular diseases, is one of the important causes of death. High blood pressure can be controlled through diet.…”

Section: Effects Of Seed Sprouts On Human Healthmentioning

confidence: 99%

Advances in Engineering and Environmental Sciences

2023

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In the ever-evolving landscape of science and technology, the fields of engineering and environmental sciences have emerged as the vanguards of innovation and sustainability. These domains intersect and intertwine, shaping the future of our world. This book is a testament to the pursuit of knowledge and progress in these crucial areas. A diverse array of topics is proposed that not only reflect the current state of these disciplines but also illuminate the path ahead. Our aim is to provide a comprehensive overview of the developments in engineering and environmental sciences, offering a valuable resource for scholars, researchers, and practitioners. The chapters contained within this book span a wide spectrum of subjects, each contributing a unique facet to the ever-expanding mosaic of knowledge. The opening chapters delve into the world of advanced materials and innovative engineering practices. Self-healing composites, with their transformative ability to repair structural damage autonomously, promise to revolutionize industries ranging from aerospace to construction. Lattice structures and FDM printed parts explore the intricate balance between design and function, pushing the boundaries of what is possible in manufacturing and construction. The next contributions traverse the frontier of biotechnology and its applications. Nanobiotechnology takes us into the realm of the infinitesimally small, where nanomaterials and techniques hold immense potential for fields such as medicine, energy, and environmental remediation. Biomaterials open doors to the development of biocompatible materials, spurring advancements in healthcare and regenerative medicine. Microbial safety underscores the importance of understanding and managing microorganisms in various environmental contexts. Other chapters explore the broader systems and environmental aspects of engineering. Server queueing models provide insights into optimizing digital infrastructures, crucial in an increasingly interconnected world. Climate-smart agriculture offers solutions to feed a growing global population while mitigating the impacts of climate change. Deep learning architectures, inspired by the human brain, unlock new horizons in artificial intelligence and data analysis. Thank you for joining us on this exciting expedition into the fields of engineering, science, and the environment. The voyage ahead is filled with challenges, but it is also packed with limitless possibilities and discoveries waiting to be made. Sincerely,Prof. Raul D.S.G. CAMPILHO

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“…Phenolic compounds show antioxidant activity in the body due to their free radical capture capacity and are associated with many diseases [ 121 ]. They also prevent oxidative DNA damage by inhibiting the binding of carcinogens to DNA.…”

Section: Phenolic Compoundsmentioning

confidence: 99%

Cruciferous Vegetables and Their Bioactive Metabolites: from Prevention to Novel Therapies of Colorectal Cancer

Ağagündüz

Şahin

Yılmaz

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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The Brassicaceae family, known as cruciferous vegetables, includes many economically important species, mainly edible oil plants, vegetable species, spice plants, and feed plants. Cruciferous vegetables are foods rich in nutritive composition and are also a good source of dietary fiber. Besides, cruciferous vegetables contain various bioactive chemicals known as glucosinolates and S-methyl cysteine sulfoxide, including sulphur-containing cancer-protective chemicals. Numerous studies have reported that daily intake of sulphurous vegetables helps prevent cancer formation and reduces cancer incidence, especially in colorectal cancer, through various mechanisms. The potential mechanisms of these compounds in preventing cancer in experimental studies are as follows: protecting cells against DNA damage, inactivating carcinogenic substances, showing antiviral and antibacterial effects, triggering apoptosis in cells with disrupted structure, inhibiting tumour cell migration causing metastasis and the development of tumour-feeding vessels (angiogenesis). These beneficial anticancer effects of cruciferous vegetables are generally associated with glucosinolates in their composition and some secondary metabolites, as well as other phenolic compounds, seed oils, and dietary fiber in the literature. This review aims to examine to the roles of cruciferous vegetables and their important bioactive metabolites in the prevention and treatment of colorectal cancer.

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Fenolik Bileşiklerin Bağlı Formları ve Biyoyararlılığı

Abstract: O. Yemiş) 0 264 295 31 92 0 264 295 56 01

Cited by 16 publications

References 91 publications

Gingko biloba L.’nın Fitokimyasal Bileşimi, Antioksidan ve Anti-Kanser Aktiviteleri Üzerine Bir Araştırma

Gingko biloba L.’nın Fitokimyasal Bileşimi, Antioksidan ve Anti-Kanser Aktiviteleri Üzerine Bir Araştırma

Advances in Engineering and Environmental Sciences

Cruciferous Vegetables and Their Bioactive Metabolites: from Prevention to Novel Therapies of Colorectal Cancer

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