2007
DOI: 10.1136/pgmj.2006.053215
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Femoral osteolysis following total hip replacement

Abstract: Total hip replacement represents the most significant advance in orthopaedic surgery in the 20th century. Periprosthetic osteolysis remains the most significant long-term complication with total hip replacement. It has been reported with all materials and prosthetic devices in use or that have been used to date. This paper reviews the current thinking on the aetiology, pathogenesis, management and future treatment options for osteolysis.

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Cited by 73 publications
(49 citation statements)
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“…According to Dattani,6 reasons for radiolucent zones around the femoral component in THA may be aging, adaptive bone remodeling, migration of the prosthesis, fluid pressure and wear debris. In combination with the other reasons mentioned above, debris, whether an ionic one from metal-on-metal tribological pairings, polyethylene, or cement, may lead to a release of proinflammatory mediators and the activation of osteoclasts.…”
Section: Discussionmentioning
confidence: 99%
“…According to Dattani,6 reasons for radiolucent zones around the femoral component in THA may be aging, adaptive bone remodeling, migration of the prosthesis, fluid pressure and wear debris. In combination with the other reasons mentioned above, debris, whether an ionic one from metal-on-metal tribological pairings, polyethylene, or cement, may lead to a release of proinflammatory mediators and the activation of osteoclasts.…”
Section: Discussionmentioning
confidence: 99%
“…It is difficult to determine the prevalence of osteolysis, as it exists in many asymptomatic patients. However, in Sweden, osteolysis was the cause of revision surgery for 75% of patients with metal‐on‐metal articulation …”
Section: Adverse Local Tissuementioning
confidence: 99%
“…Több közle-mény 30 és 60% közé teszi az osteolysis prevalenciáját 10 évnél régebben beültetett protézis esetén [2,3].…”
Section: Esetismertetésunclassified
“…Napjainkban a periprotetikus osteolysis, illetve az aszeptikus lazulás jelenti a leggyakoribb problémát a revíziós endoprotetikában [1,3,4]. Az osteolysis lokalizációjától és mértékétől, valamint a beteg életkorától és aktivitásá-tól függően több lehetőségünk van a megoldásra [1,7,10,11].…”
Section: Megbeszélésunclassified