Female genital tuberculosis: Uncommon presentation of tuberculosis in the United States

Hassoun, Ali; Jacquette, Germaine; Huang, Ada; Anderson, Ashley A.; Smith, Miriam A.

doi:10.1016/j.amjmed.2005.06.025

Cited by 25 publications

(19 citation statements)

References 11 publications

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“…Despite significant medical advances, TB is still a major factor of mortality from infectious disease [4]. Every year 8 million new TB cases are added to TB patient population and 95% of these patients from undeveloped countries [9].…”

Section: Discussionmentioning

confidence: 99%

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Menometrorrhagia Resistant To Progestin Treatment in a Secondary Infertile Woman with Pelvic Tuberculosis

2014

J Androl Gynaecol

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In the underdeveloped and developing countries, tuberculosis endometritis is still an important infectious disease and community health problem. In cases with infertility, abnormal uterine bleeding resistant to progestin treatment and family history of tuberculosis, genital tuberculosis should be kept in mind.our hospital, patient had progestin therapy for 2 months, but no regression of complaints was obtained. Her medical history revealed that patient's husband had TB infection 16 years ago.Physical examination showed nothing except vaginal bleeding associated with passage of clots. USG examination was normal and laboratory testing's revealed iron deficiency anemia. Given these findings and had a history of progestin therapy, endometrial biopsy was performed. Endometrial biopsy obtained granuloma structures with the multinuclear giant cells and epithelioid histiocytes. Patient chest x-ray showed no evidence of pulmonary TB. Considering these findings, patient accepted as TB endometritis resistant to progestin treatment and received anti-TB therapy for six months (isoniazide, rifampicin, ethambutol, pyrazinamide). Three weeks after the initiation of therapy vaginal bleeding stopped. During the multidrug therapy, there were no adverse effects. At the end of six months of therapy, control endometrial biopsy performed and normal secretory endometrium was reported. The patient was free of disease for 18 months after treatment. DiscussionDespite significant medical advances, TB is still a major factor of mortality from infectious disease [4]. Every year 8 million new TB cases are added to TB patient population and 95% of these patients from undeveloped countries [9]. Because of its different clinical manifestations, genital TB is still a major problem and difficult to diagnose for gynecologists. Genital TB can be latent for years after initial seeding and infection usually occurs by reactivation of organisms from systemic distribution of TB bacillus.Diagnostic tools vary from physical examination to isolation of TB bacillus. Although physical examination is very importance for diagnosis of genital TB, it may reveal nothing [3]. Chest x-ray is the another tool to search primary or secondary TB focus but normal

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Section: Discussionmentioning

confidence: 99%

“…Incidence of the secondary TB after the lung TB is 10% [2]. Most affected organs of the pelvic are tubes (100%), endometrium (50%), ovaries (20%), cervix (5%), respectively while vaginal and vulvar disease are very rare [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Menometrorrhagia Resistant To Progestin Treatment in a Secondary Infertile Woman with Pelvic Tuberculosis

2014

J Androl Gynaecol

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“…These bacteria enter the body through lungs. From here they can travel to any organ of the body and cause disease in that organ [3]. Female genital organs are one of the common sites to be involved in women.…”

Section: Introductionmentioning

confidence: 99%

“…Genital tuberculosis is a chronic disease and often has low-grade symptomatology, with very few specific complaints [1][2][3][4][5]. Tuberculosis (TB) is a very common disease worldwide including India.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Conventional and Modern Biomedical Tools Used for Diagnosis of Genital Tract Tuberculosis: An Overview

Kumari¹,

Goel²,

Mishra³

2013

IOSR-JPBS

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“…It affects fallopian tubes most commonly 4 and is the major factor causing occluded fallopian tubes 5 . Possible symptoms of genital tuberculosis are infertility (most common symptom), abdominal pain, abnormal vaginal bleeding, amenorrhea, vaginal discharge and post-menopausal bleeding [6][7][8][9][10] and can be clinically seen in various situations such as tuboovarian abscess 11 , salpingitis 12 , PID with other infectious agents 13 or mistaken as ovarian cancer 14 .…”

Section: Introductionmentioning

confidence: 99%

Genital Tüberküloz İlişkili Pyosalpinks: İki Olgu Sunumu

Kala¹,

Topçu²,

Güzel³

et al. 2015

Cukurova Medical Journal

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Tuberculosis is an infectious disease which typically affects the lungs and caused by Mycobacterium tuberculosis. Genital tract is commonly affected secondary to a primary lesion via peritoneal, hematogenous or lymphatic spread. It causes destruction in tissue due to granulomatous reaction and is a cause of infertility in affected patients when the infection locates on genital tract. The aim of this study was to report two cases of genital and peritoneal tuberculosis of a 20 year-old women that underwent surgery because of bilateral pyosalpinx and another case with genital and peritoneal tuberculosis of a 27year-old women that underwent surgery because of bilateral adnexal mass.

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Female genital tuberculosis: Uncommon presentation of tuberculosis in the United States

Cited by 25 publications

References 11 publications

Menometrorrhagia Resistant To Progestin Treatment in a Secondary Infertile Woman with Pelvic Tuberculosis

Menometrorrhagia Resistant To Progestin Treatment in a Secondary Infertile Woman with Pelvic Tuberculosis

Comparison of Conventional and Modern Biomedical Tools Used for Diagnosis of Genital Tract Tuberculosis: An Overview

Genital Tüberküloz İlişkili Pyosalpinks: İki Olgu Sunumu

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