Female Genital Tuberculosis Among Infertile Women and Its Contributions to Primary and Secondary Infertility

Abstract

Female genital tuberculosis (FGTB) is an infectious widespread disease among young women. This meta-analysis study aimed to investigate the prevalence of Female Genital Tuberculosis among infertile women and its contribution to primary and secondary infertility. A PubMed, MEDLINE, world cat log, Lens.org, direct Google search, Google Scholar, and Researchgate, from 1971 to July 17, 2021, were searched using the keywords; prevalence, epidemiology, urogenital tuberculosis, FGTB, infertile women, infertility complaints, and FGTB testing methods. Data extracted and meta-analysis was performed. 42 studies were selected with a total of 30918 infertile women. Of these, the pooled prevalence of FGTB was 20% (15-25%; 95%CI; I2 99.94%), and the prevalence of overall infertility, primary infertility, and secondary infertility among FGTB-population were 88%, 66% and 34%, respectively. The proportion of FGTB is remarkable among infertile women globally. The biggest burden of the disease is presented in the low-income countries followed by the lower middle-income, and upper-middle-income countries.

A 32-year global analyses on dynamic trends and geospatial visualization of genital tuberculosis and female infertility: A scientometric study

“…Female GT is a significant contributor to morbidity and infertility, particularly in regions with a high incidence of tuberculosis [ 4 ]. Most patients suffer from this disease asymptomatically or with clinically insignificant symptoms, which are diagnosed after evaluation for infertility, which affects between 60 and 80 % of women suffering from the disease [ 3 , 4 ]. In view of this problem, scientometrics allows the analysis of scientific production and its development as an information process, using quantitative methods, with the purpose of knowing the impact and characteristics of research for making strategic decisions for research funding and facilitating collaboration among researchers [ [10] , [11] , [12] ].…”

“…A meta-analysis comprising 42 studies revealed that, of the 30,918 women surveyed, roughly 20 % experienced infertility. This was predominantly observed in countries with limited resources [ 17 ].…”

“…Female genital tuberculosis (GT) is often identified in women aged 20–40 during infertility assessments. A common outcome of these cases is irreversible harm, including fallopian tube distortion or blockage, intrauterine adhesions, or inflammation-induced ovarian tissue destruction [ 3 , 4 ].…”

“…The lowest reported rates (5.7 %) are in high-income countries, while the highest (24 %) are in low-income countries. A worldwide affectation of between 8 and 12 % of couples of reproductive age is observed, with anovulation being a common cause in high-income countries, while infectious etiology is frequent in low- and middle-income countries, due to the fact that tuboperitoneal damage affects fertility [ [3] , [4] , [5] , [6] ]. The overall infertility rate among women with genital tuberculosis is reported to be 88 %, with primary and secondary infertility rates at 66 % and 34 %, respectively.…”

Tuberculose pélvica simulando tumor de ovário em jovem de 19 anos: relato de caso

“…Hospital Universitário Getúlio Vargas da Universidade Federal do Amazonas (HUGV-UFAM), Manaus -AM 2. Faculdade de Medicina da Universidade Federal do Amazonas (FM-UFAM), Manaus -AM 3.…”