Female genital tuberculosis: a clinicopathological report of 13 cases

Abstract

Female genital tuberculosis (FGTB) is a rare form of tuberculosis (TB) affecting women of reproductive age. The clinical presentation is often misleading. We retrospectively collected cases of female genital tuberculosis (FGTB) diagnosed from 2006 to 2016 at our pathology department. The mean age was 39.92 years (range of 18–74 years). Most patients had reproductive age, with 30.76% postmenopausal women. Seven cases (53.84%) were addressed for histopathological analysis for clinical malignant suspicion. The diagnosis was made on eight surgical specimens (61.53%). Nine patients (69.23%) had multifocal TB. The most involved genital organs were fallopian tubes (63.84%), followed by ovaries (46.15%), endometrium (38.46%) and the cervix (23.07%). The macroscopic aspects of all resected specimens did not show the classic appearance of caseous necrosis. We found that most patients with genital tuberculosis present with clinical suspicion of malignancy leading to aggressive surgical management.

Persistent Cutaneous Metastatic Tubercular Abscesses Revealing Multifocal Tuberculosis in an Immunocompetent Patient

“…Not only our but she was only 16 whereas genital involvement in tuberculosis usually affects women of reproductive age. In the study of Efared et al, only one patient was less old [10]. Our patient was in addition sexually inactive which supposes hematogenous spread.…”

“…Investigations regarding immunodeficiency must ; Article no.IJMPCR.52247 our patient, who did not have any respiratory complaints while CT showed signs of pulmonary Out of the organ involved, our patient had bilateral pyosalpinx. Genital involvement in tuberculosis is rare highlighting the unique presentation of our patient [10]. Not only our but she was only 16 whereas genital involvement in tuberculosis usually affects women of reproductive age.…”

“…Out of the organ involved, our patient had bilateral pyosalpinx. Genital involvement in tuberculosis is rare highlighting the unique presentation of our patient [10]. Not only our patient had bilateral pyosalpinx but she was only 16 whereas genital involvement in tuberculosis usually affects women of reproductive age.…”

Etiopathogenesis, Challenges and Remedies Associated With Female Genital Tuberculosis: Potential Role of Nuclear Receptors

“…A laparoscopy combined with hysteroscopy is the most reliable tool to diagnose FGTB; however, this is associated with perioperative complications. Laparoscopy is risky because of the presence of many adhesions, which cover the pelvic organs and may hinder the diagnosis and can increase the risk of bleeding (41,50). Hysteroscopy is associated with various complications, such as excessive bleeding, perforation, inability to distinguish and distend cavity, and flare-up of genital TB, which can cause abortions and infertility (51).…”

Latent Female Genital Tuberculosis Causes Tubal Defect Leading to Infertility

“…The silent invader of the genital tract tends to create diagnostic dilemmas and diverse findings on imaging and endoscopy. The most involved genital organs (whether solely or with other organs) have been seen to be fallopian tubes (63.84%), ovaries (46.15%), endometrium (38.46%) and the cervix (23.07%) in female genital tuberculosis but the involvement has not been documented in LGTB [2]. However, a few reports have found the endometrium to be involved the most with as high as 69% in cases of secondary infertility [3] Hysterosalpingography (HSG) is a useful tool in visualizing the abnormalities in the fallopian tubes.…”