Female Consorts of Men with Non-gonococcal Urethritis

Rosedale, N.

doi:10.1136/sti.35.4.245

Cited by 10 publications

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“…Why then is there so commonly a relapse in 10 to 20% of cases, independent of the amount of tetracyclines given ? Treatment of contacts on an empirical basis is widely accepted as necessary, but this has not been validated statistically, and no evidence has appeared to support treatment of contacts (Rosedale, 1959).…”

Section: Discussionmentioning

confidence: 99%

The role of tetracyclines in the treatment of non-specific urethritis.

Evans¹

1977

Sexually Transmitted Infections

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suMMARY An assessment of the clinical findings and treatment in 400 patients with non-specific urethritis (NSU) is reported, and the effect of treating their contacts is analysed. Three tetracyclines were compared in a randomised trial which showed that low-dose oxytetracycline (250 mg twice a day) was as effective as preparations formulated specifically for twice daily administration (triple tetracycline and sustained-release tetracycline hydrochloride). The question of multiple aetiology was explored by testing statistically whether various clinical features such as age, incubation period, severity of symptoms, and previous infection were related to outcome. No subgrouping of the condition could be found. Clinical relapse proved to be independent of empirical treatment of asymptomatic contacts, which therefore appeared not to confer any benefit on either partner. It is suggested that the infective aspect of NSU is readily controlled, and that other factors, probably psychological, determine relapse.

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Section: Discussionmentioning

confidence: 99%

The role of tetracyclines in the treatment of non-specific urethritis.

Evans¹

1977

Sexually Transmitted Infections

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“…In our present state of ignorance, the best that one can do is to examine the female partner when possible and attempt to treat any abnormality that may be found. It has been suggested that mere empirical treatment of the female partner serves no useful purpose (Rosedale, 1959). Also, in the author's experience, many male patients return to the same female partner after treatment of an episode of N.G.U.…”

Section: Other Sexually Transmitted Conditionsmentioning

confidence: 96%

Immigrants to the United Kingdom and venereal infections

Rosedale

1965

Postgraduate Medical Journal

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“…The incidence of T. vaginalis in males with urethritis has been studied by a number of workers (Feo, Varano, andFetter, 1956: Symposium on Trichomonal Infestations, 1957;Lanceley, 1953Lanceley, , 1958Burgess, 1959;Rosedale, 1959;Sylvestre, Belanger, and Gallai, 1960;Willcox andRosedale, 1962, Wisdom andDunlop, 1965). From these studies it is apparent that the incidence of trichomonal urethritis in the male is variable.…”

Section: (D) Trichomonas Vaginalismentioning

confidence: 99%

Non-specific urethritis and the tetracyclines.

Grimble¹,

Amarasuriya²

1975

Sexually Transmitted Infections

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Non-specific urethritis (NSU) is treated as an entity, yet it includes cases of urethral inflammation presumed to be related to the presence of probably several specific organisms. The effectiveness of the tetracycline group of antibiotics in comparison with other forms of treatment is not in doubt (Wilcox, 1972). In the present study we wish to remark upon the aetiology of NSU and to discover whether tetracycline treatment can assist us in understanding the nature of NSU, and also to comment on the best application of tetracycline therapy.NSU Sompolinsky, Harari, Solomon, Caspi, Krakowski, and Henig, 1973;Wentworth, Bonin, Holmes, Gutman, Wiesner, and Alexander, 1973). Yet the role of this agent, although probably at times a pathogen, is still questionable (Richmond, Hilton, and Clarke, 1972;Hilton, Richmond, Milne, Hindley, and Clarke, 1974;Oriel, Powis, Reeve, Miller, and Nicol, 1974).It may be that Chlamydia agent plays an 'opportunist' role, and acts both as pathogen and as 'potential pathogen' in the genito-urinary tract. Much of this work is relatively new and still continuing. A recent study on the presence of antibodies to Chlamydia in patients with urethritis, and in persons without urethritis, does not make the position any clearer (Reeve, Gerloff, Casper, Philip, Oriel, and Powis, 1974). Mycoplasma hominis (and to a much lesser extent M. fermentans and M. salivarius) and T-strain mycoplasma can be present in those with a healthy genito-urinary epithelium as well as in those in whom the epithelium is inflamed. It would appear from the evidence that the T-strain may be present in over 60 per cent. of cases of urethritis, and M. hominis in about 20 per cent. of cases.

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Female Consorts of Men with Non-gonococcal Urethritis

Abstract: cases no treatment was given to patients in whom 245 copyright.

Cited by 10 publications

References 0 publications

The role of tetracyclines in the treatment of non-specific urethritis.

The role of tetracyclines in the treatment of non-specific urethritis.

Immigrants to the United Kingdom and venereal infections

Non-specific urethritis and the tetracyclines.

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