Felty's Syndrome with Chronic Hepatitis and Compatible Autoimmune Hepatitis: A Case Presentation

Abstract

A 68-year-old woman with Felty's syndrome was admitted to our hospital due to breathlessness. She was diagnosed as having rheumatoid arthritis at age 59 years.

Surgical management of portal hypertension in Felty’s syndrome: A case report and literature review

“…In the present case, we are convinced that increasing blood flow to the spleen due to splenomegaly caused portal hypertension, congestion of blood within the liver, and chronic hepatitis gradually worsened to liver failure [28]. "…”

“…A recent interesting addition to the literature by Sema et al [28] reports a case of Felty's syndrome with chronic hepatitis and compatible autoimmune hepatitis in which the patient had a contracted liver, ascites, tortuous enlarged splenic vein, and splenomegaly and esophageal varices with subsequent banding [28]. The patient died from hepatic failure with encephalopathy.…”

Gastrointestinal and Hepatic Disease in Rheumatoid Arthritis

“…About two thirds of patients develop hepatomegaly, and more than half have at least one abnormal liver function test. 91,92 Several findings have been described on biopsy, including nodular regenerative hyperplasia (NRH), sinusoidal lymphocytosis, and portal hypertension related to splenomegaly. 92,93 About 35% of patients with Felty’s syndrome with an abnormal liver enzyme have been found to have NRH on autopsy.…”

Leberwerterhöhung bei rheumatoider Arthritis

“…Im vorliegenden Fall wurden mehrere mögliche Ursachen für die deutliche Leberwerterhöhung in Betracht gezogen: die nichtalkoholische Fettleberhepatitis (NASH), die akut-toxische Hepatitis und die Autoimmunhepatitis (AIH), die mit rheumatischen Erkrankungen assoziiert sein kann [10,11,21,26].…”