Feline sporotrichosis: A case report

Cabo, J. F. González; Guillamón, Marcelo de las Heras; Cequiel, M. V. Latre; Ciércoles, José Antonio García de Jalón

doi:10.1007/bf00436219

Cited by 25 publications

(15 citation statements)

References 6 publications

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“…Studies using saturated potassium iodide solution (SSKI) have shown variable cure efficiency in felines with sporotrichosis (Dunstan et al., 1986; Gonzalez Cabo et al., 1989; Caravalho et al., 1991). Studies using ketoconazole, an anti‐fungal of the imidazole group, used in clinical cases of disseminated cutaneous sporotrichosis by Marques et al.…”

Section: Resultsmentioning

confidence: 99%

“…The deceased felines had the disseminated cutaneous form and these two showed an extreme physical weakness, whereas one was in apparent good condition at the time of death. Studies using saturated potassium iodide solution (SSKI) have shown variable cure efficiency in felines with sporotrichosis (Dunstan et al, 1986;Gonzalez Cabo et al, 1989;Caravalho et al, 1991). Studies using ketoconazole, an anti-fungal of the imidazole group, used in clinical cases of disseminated cutaneous sporotrichosis by Marques et al (1993) and Nobre et al (2001), demonstrated inefficiency for the treatment of mycosis in felines.…”

Section: Resultsmentioning

confidence: 99%

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Feline Sporotrichosis in the Southern Region of Rio Grande Do Sul, Brazil: Clinical, Zoonotic and Therapeutic Aspects

Madrid

Mattei

Martins

et al. 2010

Zoonoses and Public Health

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Clinical cases of feline sporotrichosis, originating in the Pelotas region and diagnosed at the Laboratory of Infectious Diseases (UFPel), were studied in the period from 2002 to 2006. The animals were evaluated according to the clinical forms of the mycosis, time of lesion appearance, severity of the clinical diagnosis and evolution of cutaneous lesions throughout the treatment period. Mycological analyses, carried out through direct examination, cultivation of tissue samples and exudates of feline lesions all confirmed the diagnosis of sporotrichosis in the 15 animals under study. The cutaneous dissemination form was observed in 10 animals, of which three showed prostration, anorexia and dehydration. The zoonosis occurred in 20% of case studies, and the pet owners and one attendant at a veterinary clinic were infected, developing the fixed and disseminated cutaneous forms. The treatment of mycosis was carried out with itraconazole, 10 mg kg(-1), once a day, on 12 animals. The cure of the clinical symptoms was observed on 50% of the felines. This study demonstrates a good clinical response of felines with sporotrichosis, when they were treated itraconazole and calls the attention for the incidence of human sporotrichosis on people related to the veterinary activity as well as for pet owners.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Feline Sporotrichosis in the Southern Region of Rio Grande Do Sul, Brazil: Clinical, Zoonotic and Therapeutic Aspects

Madrid

Mattei

Martins

et al. 2010

Zoonoses and Public Health

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“…However, the occurrence of respiratory signs is associated with treatment failure, according to previous [20][21][22] even though others have claimed treatment to be unsuccessful. 23,24 This study describes a large and wellcharacterized case series of cats treated with KI capsules, including a larger sample size, a different pharmaceutical form (capsules) and dose.…”

Section: Discussionmentioning

confidence: 99%

Potassium iodide capsule treatment of feline sporotrichosis

Reis

Gremião

Kitada

et al. 2012

Journal of Feline Medicine and Surgery

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Sporotrichosis is a mycosis caused by Sporothrix schenckii. The most affected animal is the cat; it has played an important role in the zoonotic transmission of this disease, especially in Rio de Janeiro, Brazil, since 1998. In order to evaluate the treatment of feline sporotrichosis with potassium iodide, an observational cohort was conducted in 48 cats with sporotrichosis at Instituto de Pesquisa Clínica Evandro Chagas, Fiocruz. All cats received potassium iodide capsules, 2.5 mg/kg to 20 mg/kg q24h. The cure rate was 47.9%, treatment failure was 37.5%, treatment abandonment was 10.4% and death was 4.2%. Clinical adverse effects were observed in 52.1% of the cases. Thirteen cats had a mild increase in hepatic transaminase levels during the treatment, six of them presented clinical signs suggestive of hepatotoxicity. Compared to previous studies with itraconazole and iodide in saturated solution, potassium iodide capsules are an alternative for feline sporotrichosis treatment.

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“…The lesion disappeared after oral administration of ketoconazole [8]. Another report revealed improvement by oral administration of 20% potassium iodide [4]. Iodide is reasonable in cost, but cats show greater susceptibility to the development of toxic side effects from iodides [3].…”

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A Case of Feline Sporotrichosis

Hirano

Watanabe

Murakami

et al. 2006

The Journal of Veterinary Medical Science

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ABSTRACT. We excised surgically a feline granulomatous lesion and performed histopathological, mycological and molecular examinations. As a result, it was diagnosed as sporotrichosis, which was the second recorded case of a cat so afflicted in Japan. After the operation, we recognized another nodule on the lymph node. Histopathological examination was therefore performed, but no fungi were detected. To prevent recurrence, the cat was administered a antimycotic drug, itraconazole. As a result, no recurrence was found. Excision of the lesion is the treatment of choice for feline sporotrichosis. KEY WORDS: feline, itraconazole, sporotrichosis.J. Vet. Med. Sci. 68(3): 283-284, 2006 Fungi are widespread in the environment and not usually harmful to healthy animals. However, the number of mycosis cases has recently increased in animals in which the immunity has been decreased by antineoplastic drugs or immunosuppressive drugs. A report has indicated the zoonotic potential of some animal fungi around the world [9]. Sporotrichosis is caused by the dimorphic fungus, Sporothrix schenckii. There have been many reports of infections in horses, cats and humans [2,5,7]. Sporothrix schenckii is isolated from soils, sphagnum moss and tree bark. It infects animals and humans through a puncture wound. Sporotrichosis can be divided into three clinical forms: cutaneolymphatic, cutaneous, and disseminated [3]. In Japan there have been many cases of sporotrichosis in humans, but only one case report of feline sporotrichosis [8].This case was a 2-year-old male mongrel house cat with free outdoor access, weighing 5.4 kg, which had been treated for skin abscesses. This cat was referred to Gifu University Teaching Animal Hospital with a subcutaneous nodule on the right hind leg, which had gradual growth. The cat was in good general condition. A nodule was recognized near the main pad on the right hind leg. We excised it surgically under general anesthesia. The nodule, 18 × 15 × 6 mm in size, was brown and smooth, and was well-demarcated (Fig. 1). The histopathological finding indicated many yeast-like cells with granulomatous inflammation (Fig. 2), so culture and molecular examinations were performed for the biopsy material from the nodule. As a result, the isolate was identified as S. schenckii. And the case was diagnosed as sporotrichosis by S. schenckii-specific polymerase chain reaction analyses, too [6].Nine days after the operation, we recognized another nodule on the right popliteal lymph node. We excised it surgically, but no fungi were detected in it. According to the diagnosis of sporotrichosis, 34 days after the operation, the cat was administered itraconazole (15 mg/kg once daily, per os) to avoid recurrences. After 50 postoperative days, we also recognized another nodule on the left popliteal lymph node, and performed a fine needle aspiration biopsy because there was a possibility of metastasis. However it was not diagnosed. At 69 days postoperation, the left popliteal lymph node showed a slight decrease in size, but the ...

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Feline sporotrichosis: A case report

Cited by 25 publications

References 6 publications

Feline Sporotrichosis in the Southern Region of Rio Grande Do Sul, Brazil: Clinical, Zoonotic and Therapeutic Aspects

Feline Sporotrichosis in the Southern Region of Rio Grande Do Sul, Brazil: Clinical, Zoonotic and Therapeutic Aspects

Potassium iodide capsule treatment of feline sporotrichosis

A Case of Feline Sporotrichosis

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