Feline papillomavirus-associated Merkel cell carcinoma: a comparative review with human Merkel cell carcinoma
James K CHAMBERS,
Soma ITO,
Kazuyuki UCHIDA
Abstract:Merkel cell carcinoma (MCC) is a rare skin tumor that shares a similar immunophenotype with Merkel cells, although its origin is debatable. More than 80% of human MCC cases are associated
with Merkel cell polyomavirus infections and viral gene integration. Recent studies have shown that the clinical and pathological characteristics of feline MCC are comparable to those of
human MCC, including its occurrence in aged individuals, aggressive behavior, histopathological findings, and the expression of Merkel cell … Show more
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