Feline hypertrophic cardio‐myopathy: Variations on a theme

Abstract

The history and the physical, radiographic, electrocardiographic, echocardiographic, haemo‐dynamic and angiocardiographic findings from 18 cats with idiopathic hypertrophic cardiomyopathy are described. These data document a diverse spectrum of clinical manifestations of this disease in cats. The variety and complexity of feline hypertrophic cardiomyopathy complicate the diagnosis and challenge the idea that this disorder is a single disease entity.

Prevalence of the MYBPC3-A31P mutation in a large European feline population and association with hypertrophic cardiomyopathy in the Maine Coon breed

“…The overrepresentation of affected males in the feline species and in the Maine Coon breed has already been discussed. 27,28 Factors like modifier genes or hormones may have a bearing on the sexual predisposition to HCM as has been reported in humans with HCM or other heart diseases. 29,30 In conclusion, the MYBPC3-A31P mutation is highly prevalent in European Maine Coon cats and seems specific to this feline breed although potential marginal events may occur.…”

Echocardiographic Evaluation of the Left Ventricle Filling Pressure

“…However, some cats can develop severe CHF in the absence of major echocardiographic anomalies [38]. However, some cats can develop severe CHF in the absence of major echocardiographic anomalies [38].…”

Evaluation of Feline Cardiomyopathies

“…A study performed on 18 cats with HCM reported concomitant right ventricular free wall hypertrophy in 11% of the cases [5].…”

“…HCM is characterized by myocardial hypertrophy affecting mostly the left ventricle (LV) and sometimes the right ventricle (RV) [5]. This hypertrophy can take very diverse aspects [6].…”