Feline herpesvirus

Abstract

-Feline herpesvirus (FHV-1; felid herpesvirus 1 (FeHV-1)) is an alphaherpesvirus of cats closely related to canine herpesvirus-1 and phocine herpesvirus-1.

Epidemiological status of felid herpesvirus type-1 and feline calicivirus infections in Brazil

“…Feline herpesvirus type-1 (FeHV-1) FeHV-1 is the infectious agent responsible for feline viral rhinotracheitis [FVR] (GASKELL et al, 2007). The initial isolation of FeHV-1 was described in 1957 in North America, and strain "C-27" was referred to as the virus prototype (CRANDELL & MAURER, 1958).…”

“…FeHV-1 consists of double-stranded DNA of 134 kilobases (Kb) with icosahedral capsids surrounded by a lipid envelope, presence of tegument between envelope and the capsid, and the diameter of virions range from 120 to 300nm (POVEY, 1979;GASKELL et al, 2007). The genome encodes five envelope glycoproteins that are important in the induction of humoral and cellular immunity (MAEDA et al, 1998).…”

“…The genome encodes five envelope glycoproteins that are important in the induction of humoral and cellular immunity (MAEDA et al, 1998). Some FeHV-1 isolates may differ in virulence, although all of them belong to one serotype (GASKELL et al, 2007).…”

“…FeHV-1 is distributed worldwide and endemic in most populations (GASKELL et al, 2007). The information available in Brazil consists of serological studies in wild and domestic cats (RUTHNER-BATISTA et al, 2005;FILONI et al, 2006;JOHANN et al, 2009;HENZEL et al, 2013), and isolation of FeHV-1 in RS (HENZEL et al, 2012b).…”

“…Members of the Felidae family are the susceptible hosts, and there are no age, sex or breed predispositions to infection; however, the infection is more severe in cats of up to six months of age (POVEY 1979;GASKELL et al, 2007). The prevalence varies according to the population density; it may be lower than 1% in small groups and between 10 to 20% in large populations (GASKELL et al, 2007).…”