Feline cutaneous squamous cell carcinoma of the nasal planum and the pinnae: 61 cases

Abstract

Cutaneous squamous cell carcinoma is a common tumor in cats and frequently occurs on the nasal planum and the pinnae. The medical records of 61 cats were reviewed for this retrospective study. Typical presentation was an older (median age, 12 years) cat with an erythematous, crusty, and erosive lesion. Methods of treatment included surgery, radiation, and cryotherapy. Disease-free interval and survival time were calculated for each case and grouped according to lesion location and treatment type. All treatments were found to be effective, with surgery resulting in the longest disease-free interval (median, 594 days).

Ki67 Reactivity in Nasal and Periocular Squamous Cell Carcinomas in Cats Treated with Electron Beam Radiation Therapy

“…Nevertheless, the number of cats diagnosed with local or distant metastasis in our study was higher than in other studies. 2,[4][5][6]8 Whether aggressive treatment could have influenced the metastatic rate (eg. by upregulating growth factors) is unknown but possible.…”

“…In contrast to surgery, radiation therapy was found to be a cosmetically appealing and effective option. 4,[6][7][8] Squamous cell carcinomas are thought to be rapidly dividing tumors. A potential tumor doubling time of approximately 5 days was determined by using flow cytometry and bromodeoxyuridine (BrdU) staining.…”

A utilização da radioterapia no tratamento do carcinoma de células escamosas cutâneo felino avançado

“…Também, a maioria dos animais era proveniente de locais com alta exposição à luz solar, como casas com quintal e rua, confirmando o fato de que a carcinogênese está envolvida com a radiação solar e que animais de pelagem branca são mais propensos do que os de outras cores (Carpenter et al, 1987;Cox, 1991;Miller et al, 1991;Lana et al, 1997;Moore e Ogilvie, 2001;Cunha et al, 2010).…”

“…Essa média se assemelha aos achados anteriores e confirma que gatos idosos são mais propensos ao CCE cutâneo. A explicação para isso é que a carcinogênese actínica é lenta, podendo durar anos (Miller et al, 1991;Lana et al, 1997).…”

Ear

“…38 Surgical excision is curative for peripheral lesions and allows the histologic assessment of margins. 38 Surgical excision is curative for peripheral lesions and allows the histologic assessment of margins.…”