Fehldiagnostiziertes mikrozystisches Adnexkarzinom an der seitlichen Stirn und Herausforderungen bei der Rekonstruktion eines bis zum Knochen reichenden Defekts

Abstract

We confirm the histological difficulties in the diagnosis of this tumor entity and the large extension of MAC due to delay in diagnosis and treatment. Deep tumor removal including the periostium might be necessary to achieve tumor free margins. Fast granulation tissue above the frontal bone might be achieved by applying hyaluronic acid products. The combination an AT flap with transplantation of the adjacent Burow's triangles gives optimal skin texture and color matching and seems to be a good option to close even large defects of the front especially for supra brow defects.

Periocular Microcystic Adnexal Carcinoma: A Case Report and a Major Review

“…8,19,31,50,[64][65][66] Biopsy/debulking without definitive resection was performed in 9 (10%) patients. 2,8,24,29,30,40,55,61 Regional lymph node dissection was undertaken in 4 (4%) patients. 31,56,59,66 Eight (9%) patients underwent adjuvant radiotherapy.…”

“…Information on the duration of follow-up was available on 64 of 93 patients (69%). 2,3,5,8,9,[11][12][13][14][15][16]18,[20][21][22][24][25][26][27][28][29][30][31][32][33][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][53][54][55][57][58][59][61][62][63][64][65][66]…”

“…Review of the literature identified 92 patients fulfilling the inclusion criteria for this study in addition to our current patient, for a total of 93 patients with MAC. 2,3,5,8,9,11–69 Patient demographics and presenting characteristics are summarized in Table 1.…”

“…Of patients with available information, most tumors presented as brown-to-reddish (5/18, 28%) 32,54,57,59,62 or pearly white-to-waxy (7/18, 39%) 8,24,33,40,52,58,68 nodules (37/68, 54%) 2,3,5,9,11,14–16,19,23–26,32,33,35,37,43,46,48,52,54,56,59,66,67,69 or plaques (20/68, 29%) 8,13,17,18,21,22,24,28,29,42,47,54,58,59,61–63,68 that were ill-defined, sclerotic, or indurated (20/51, 39%) 3,13,25,26,32,33,42,46,47,56,57,59,62,63,68 with firm consistency (19/51, 37%), 2,8,13,23,24,28,36,37,47,54,56,68 10 mm or greater in size (33/46, 72%). 3,6,11,13,14,17,18,24,25,29,35,37,42,47,49,51,52,…”

“…Information on the duration of follow-up was available on 64 of 93 patients (69%). 2,3,5,8,9,11–16,18,20–22,24–33,36–51,53–55,57–59,61–69 The average total period of observation from the time of initial presentation to the final documented care was 8 years (median 5, range 0.2–70 years), and the average follow-up after last documented treatment was 3 years (median 2, range 0.2–20 years). Follow-up information was available on 87 of 93 (94%) patients.…”