Feelings of anxiety and associated variables in a very elderly population

Forsell, Yvonne; Winblad, Bengt

doi:10.1002/(sici)1099-1166(199807)13:7<454::aid-gps795>3.0.co;2-d

Cited by 43 publications

(14 citation statements)

References 18 publications

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“…The highest scores were reported for apathy, anxiety, and depression. The rates found were similar to those reported in previous studies, focusing on depression,1hallucinations,2 anxiety,13 and apathy14 and are well above the frequencies found in the general, non-parkinsonian elderly population in Scandinavia15 16 …”

Section: Discussionsupporting

confidence: 90%

Range of neuropsychiatric disturbances in patients with Parkinson's disease

Aarsland¹,

Larsen

Lim

et al. 1999

Journal of Neurology, Neurosurgery & Psychiatry

521

396

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Objectives-Disturbances of cognition and emotion are common in patients with Parkinson's disease. Most previous studies of psychopathology in Parkinson's disease have focused on a single psychiatric diagnosis or condition. The objective of this study was to describe the range of neuropsychiatric symptoms in a representative sample of patients with Parkinson's disease. Methods-The sample of 139 patients was drawn from an epidemiological study of Parkinson's disease in Rogaland county, Norway, and represented 93% of those who had survived during the 4 years since the initial assessment. The diagnosis of Parkinson's disease was based on published criteria. Neuropsychiatric symptoms were assessed using the neuropsychiatric inventory, a caregiver based structured interview, which assesses severity and frequency of 10 psychiatric symptoms present during the past month. Results-At least one psychiatric symptom was reported in 61% of the sample. The most common behaviours were depression (38%) and hallucinations (27%), and the least common symptoms were euphoria and disinhibition. The highest mean scores were found for depression, apathy, and hallucinations. Factor analysis showed that hallucinations, delusions, and irritability clustered into one factor, and apathy and anxiety constituted another factor. Psychiatric symptoms were more common among patients living in nursing homes compared with home dwelling patients, and correlated with stage of disease and cognitive impairment, but not with age or duration of disease. No relation to left or right sided parkinsonism was found. Conclusion-This study emphasises the importance of psychiatric symptoms in Parkinson's disease, which were present in most patients. Clinicians should focus on the emotional and cognitive disturbances in addition to the motor manifestations of the disease. (J Neurol Neurosurg Psychiatry 1999;67:492-496)

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Section: Discussionsupporting

confidence: 90%

Range of neuropsychiatric disturbances in patients with Parkinson's disease

Aarsland¹,

Larsen

Lim

et al. 1999

Journal of Neurology, Neurosurgery & Psychiatry

521

396

View full text Add to dashboard Cite

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“…[19] They conclude that subthreshold anxiety disorders may present commonly among older adults and that these cases are typically not being recognized. More research is needed to elucidate the patterns of reporting among older adults that may lead to non-diagnosis.…”

Section: 205mentioning

confidence: 99%

Anxiety disorders in older adults: a comprehensive review

Wolitzky-Taylor¹,

Castriotta²,

Lenze³

et al. 2010

Depress. Anxiety

548

398

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This review aims to address issues unique to older adults with anxiety disorders in order to inform potential changes in the DSM-V. Prevalence and symptom expression of anxiety disorders in late life, as well as risk factors, comorbidity, cognitive decline, age of onset, and treatment efficacy for older adults are reviewed. Overall, the current literature suggests: (a) anxiety disorders are common among older age individuals, but less common than in younger adults; (b) overlap exists between anxiety symptoms of younger and older adults, although there are some differences as well as limitations to the assessment of symptoms among older adults; (c) anxiety disorders are highly comorbid with depression in older adults; (d) anxiety disorders are highly comorbid with a number of medical illnesses; (e) associations between cognitive decline and anxiety have been observed; (f) late age of onset is infrequent; and (g) both pharmacotherapy and CBT have demonstrated efficacy for older adults with anxiety. The implications of these findings are discussed and recommendations for the DSM-V are provided, including extending the text section on age-specific features of anxiety disorders in late life and providing information about the complexities of diagnosing anxiety disorders in older adults. Depression and Anxiety 27:190-211, 2010.

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“…Symptoms assessed by the anxiety subscale include nervousness, trembling, fear, panic, restlessness, and frightening thoughts and is therefore a brief composite measure of psychic and somatic anxiety symptoms. Participants indicate how affected they have been by each symptom over a seven day period, ranging from not at all (0), a little bit (1), moderately (2), quite a bit (3) to extremely (4). While the SCL-90-R is not frequently used for mood assessment in atherosclerotic patients, these SCL-90-R subscales are valid and reproducible measures of anxiety and depression symptoms (25–30).…”

Section: Methodsmentioning

confidence: 99%

“…Anxious symptoms, while common, are under-recognized in the elderly (1, 2, 3). Anxiety has been linked to future risk of cardiovascular (CV) events, with a hazard ratio of 1.26 for cardiovascular events in one meta-analysis (4).…”

Section: Introductionmentioning

confidence: 99%

Association of Anxiety With Resistance Vessel Dysfunction in Human Atherosclerosis

Stillman

Moser

Fiedorowicz

et al. 2013

Psychosomatic Medicine

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Objective Anxiety predicts cardiovascular events, though the mechanism remains unclear. We hypothesized that anxious symptoms will correlate with impaired resistance and conduit vessel function in participants aged 55–90 years. Method Anxious symptoms were measured with the Symptom Checklist-90-Revised in 89 participants with clinically diagnosed atherosclerotic cardiovascular disease and 54 healthy control participants. Vascular function was measured in conduit arteries using brachial flow-mediated dilatation (FMD) and in forearm resistance vessels (FRV) using intra-arterial drug administration and plethysmography. Results Anxious symptoms were not associated with FMD in either group. Participants with atherosclerosis exhibited significant inverse associations of anxious symptoms with FRV dilatation (β for acetylcholine =−0.302, p=0.004). Adjustment for medication, risk factors and depressive symptoms did not alter the association between anxiety and FRV dysfunction, except for BMI (anxiety β=−0.175, p=0.060; BMI β=−0.494, p<0.001). While BMI was more strongly associated with FRV function than anxiety, combined BMI and anxiety accounted for more variance in FRV function than either separately. Control participants showed no association of anxiety with FRV function. Conclusion Anxiety is uniquely and substantially related to poorer resistance vessel function (both endothelial and vascular smooth muscle function) in individuals with atherosclerosis. These relationships were independent of medication, depression and cardiovascular risk factors, with the exception of BMI. These findings support the concept that anxiety potentially increases vascular events through worsening of vascular function in atherosclerotic disease.

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Feelings of anxiety and associated variables in a very elderly population

Cited by 43 publications

References 18 publications

Range of neuropsychiatric disturbances in patients with Parkinson's disease

Range of neuropsychiatric disturbances in patients with Parkinson's disease

Anxiety disorders in older adults: a comprehensive review

Association of Anxiety With Resistance Vessel Dysfunction in Human Atherosclerosis

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