Feeding zilpaterol hydrochloride is associated with decreased dry matter intake shortly after initiation of feeding dependent on season and previous intake1

Reinhardt, C. D.; Vahl, Christopher I.; Depenbusch, Brandon E.; Hutcheson, J. P.; Thomson, Daniel U.

doi:10.2527/jas.2014-7562

Cited by 10 publications

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References 55 publications

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“…Some studies reported no change in DMI when animals are fed with ZH (ELAM et al, 2009;ROBLES-ESTRADA et al, 2009;PARR et al, 2011), while others have reported a decrease in DMI after administration of ZH (REINHARDT et al, 2014;. In the present study heifers fed ZH had similar DMI to control heifers, which, associated with the greater ADG, resulted in improved feed efficiency.…”

Section: Discussionsupporting

confidence: 49%

<b>Uso de agonista β-adrenérgico na dieta de bovinos de corte</b>

Cônsolo¹

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Dedico esse estudo, todo meu trabalho e esforço para as pessoas que mais amo nessa vida, pois sem eles nada disso e nada de mim seria possível. Ao meu grande Pai Tarcísio Cônsolo À minha forte Mãe Fátima Maria Brandão Cônsolo À minha queridíssima Irmã Lara Cristina Brandão Cônsolo AGRADECIMENTOS Agradeço a Deus, pela vida, força, dedicação, sabedoria, oportunidades e condição para realização dos meus sonhos. Ao meu Pai Tarcísio, minha Mãe Fátima e minha Irmã Lara por serem parte de mim, por me apoiar, me dar força sempre me dar bons conselhos, me direcionar e sobre tudo me acalmar em momentos difíceis. Ao meu orientador Prof. Dr. Luis Felipe Prada e Silva, que me deu a liberdade de confiança para trabalhar. À todos os professores e funcionários do Departamento de Nutrição e Produção Animal (VNP). Ao meu querido grupo de trabalho LPGC, aos funcionários e amigos que fizeram parte do meu trabalho. Aos demais amigos de Departamento que fizeram meu Doutorado mais feliz. Aos funcionários da empresas que financiaram essa pesquisa, MDS Saúde Animal e Ouro Fino Saúde Animal. A Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), pela concessão da bolsa de estudo, que gerou tranquilidade e possibilitou a dedicação intensa e exclusiva a este trabalho. Às pessoas especiais que fizeram e fazem parte da minha jornada na Pós-Graduação: Análises sensoriais. Aos queridos funcionários, à Lígia Mesquita, e aos queridos amigos do Laboratório de Pesquisa em gado de Corte. "Se ficar saudade Deixa que mais tarde ela também vai Como vai a vida Vou tocando em frente sem olhar pra trás Coisas que acontecem Deixa que eu lhe diga, nada me cansou Não senti fadiga Porque gente amiga só me traz calor Se eu tô indo embora Não vai ser agora que se vai sofrer Deixa que mais tarde Na curva da estrada a gente se vê Se eu deixo saudade Vou levar também Ter que ir embora Todo mundo tem" Almir Sater e Renato Teixeira RESUMO CÔNSOLO, N. R. B. Uso de agonista β-adrenérgico na dieta de bovinos de corte. 2015. 85 f. Tese (Doutorado em Ciências) -Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, 2015. O objetivo desse estudo foi avaliar o efeito do Cloridrato de Zilpaterol (ZH), Ractopamina (RH) e aumento no nível de proteína da dieta, em dois experimentos distintos na dieta de animais Nelore em sistema de confinamento, nas características produtivas, metabólitos sanguíneos, características de carcaça, composição de corpo vazio e ganho, qualidade da carne e expressão gênica. Para isso, foram realizados dois experimentos. O Exp. 1 utilizou 48 machos, não castrados, distribuídos em blocos casualisados em 4 tratamentos em arranjo fatorial 2x2, sendo dois níveis de PB: 100 e 120% e dois níveis de RH: 0 e 300mg/animal/dia. No Exp. 2, foram utilizadas 72 novilhas da raça Nelore distribuídas em delineamento em blocos casualizados. As novilhas foram separadas em dois grupos: Controle (CONT) e Zilpaterol (ZH). Em ambos os experimentos, os animais foram pesados periodicamente e amostras de sangue foram coletadas. Após o a...

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Section: Discussionsupporting

confidence: 49%

<b>Uso de agonista β-adrenérgico na dieta de bovinos de corte</b>

Cônsolo¹

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“…Collectively, findings from previous research combined with the DMI fluctuations observed in concert with changes in THI on the current study further support the use of tools such as THI and the Heat Load Index (Gaughan et al, 2008) to predict heat periods of heat stress. Reinhardt et al (2014) analyzed feed intakes from more than 1,500 pens from 3 different commercial Kansas feedlots and reported reduced DMI shortly after initiation of ZIL administration, especially during summer months. The findings of the current study support this, as DMI was lower and the decrease in DMI was greater in unshaded compared to shaded cattle when pooled across d 2 through 9 (P < 0.01; Fig.…”

Section: Resultsmentioning

confidence: 99%

“…Still, our findings suggest shade mitigated the decrease in DMI after ZIL administration, which warrants further discussion. Although the exact mechanism for the decrease in DMI after commencement of ZIL is not completely understood, Reinhardt et al (2014) proposed βAAinduced metabolic alterations leading to increased glycogenolysis and lactate production, hepatic preference of propionate from grain-fed diets as the substrate for gluconeogenesis, and consequent build-up of lactate concentrations resulting in secondary intake depression as one possible cause. Moreover, the original Zilmax label called for inclusion based on g/ton only, resulting in DMI as the lone determinant of actual amount of ZIL consumed.…”

Section: Resultsmentioning

confidence: 99%

“…Moreover, the original Zilmax label called for inclusion based on g/ton only, resulting in DMI as the lone determinant of actual amount of ZIL consumed. Given this fact, it is foreseeable that doses of ZIL greater than approved Reinhardt et al, 2014). Shaded cattle had greater (P = 0.01) pooled mean DMI over d 2 -9 after initiation of ZIL administration, however the shade × day interaction was insignificant (P = 0.38).…”

Section: Resultsmentioning

confidence: 99%

“…The DMI and the change in DMI were evaluated between shade treatments from before initiation of ZIL through d 2 to 9 after commencement of ZIL administration (post-ZIL) using procedures similar to Reinhardt et al (2014) with day post-ZIL was treated as a repeated measure using an autoregressive covariance structure. Dry matter intake before initiation of ZIL (baseline) was calculated using the mean DMI for 5 d before beginning ZIL.…”

Section: Discussionmentioning

confidence: 99%

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Effect of shade on animal welfare, growth performance, and carcass characteristics in large pens of beef cattle fed a beta agonist in a commercial feedlot1

Hagenmaier

Reinhardt

Bartle

et al. 2016

Journal of Animal Science

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Feedlot cattle ( = 1,395; BW = 568 ± 43 kg) were used to evaluate the effects of shade on animal welfare, growth performance, and carcass quality during the summer of 2013 in a Kansas commercial feedlot. Seven lots of predominately black steers and heifers (4 and 3, respectively) visually determined to be approaching the final mo on feed were identified, randomly gate-sorted, and allocated to pens located across the feed alley from each other to receive 1 of 2 treatments: 1) Shade (mean shade area = 1.5 m/ animal) or 2) No shade. Shade was provided using a 13-ounce polyethylene fabric and pens were oriented northwest to southeast. The mean starting date was June 13 and the mean days on feed for lots while on the study was 38 d. Cattle were fed a 77.67% DM steam-flaked corn-based diet and had ad libitum access to water throughout the duration of the trial. Zilpaterol hydrochloride (ZIL) was included in the finishing ration at an inclusion rate of 8.3 mg/kg of DM for the last 20 d on feed with a 3 d withdrawal period. Pen floor temperatures (PFT) were measured using an infrared thermometer and prevalence of cattle open-mouth breathing (OMB) was recorded on a pen basis. In addition to shade treatment, the effect of temperature humidity index (THI) on PFT and OMB was analyzed by classifying days as either "Alert" (THI < 79) or "Danger" (THI > 79). On the day of slaughter, pens within a replicate were kept separate through all stages of the marketing channel from loading at the feedlot until stunning at the plant. Pen served as the experimental unit for all measurements. There was a THI × shade treatment interaction for PFT and OMB ( < 0.001) where days classified as "Danger" increased PFT and prevalence of OMB compared to "Alert" days in unshaded but not shaded cattle. Shaded cattle had greater DMI ( = 0.01); however, unshaded cattle had greater G:F ( = 0.05) and therefore no differences were observed in ADG ( = 0.39). Shaded cattle had greater dressing percentage ( = 0.01), although HCW, LM area, fat thickness, marbling score, and quality grade did not differ between treatments ( > 0.05). Heat stress, a significant animal welfare concern and cause of reduced performance in feedlot cattle during the final phase of the feeding period, was alleviated in shaded cattle and illustrates the importance of shade provision as 1 tool to protect the welfare and increase feed consumption in large pens of feedlot cattle during hot summer months.

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Beef cattle welfare in the USA: identification of priorities for future research

Tucker

Coetzee

Stookey

et al. 2015

Anim. Health. Res. Rev.

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This review identifies priorities for beef cattle welfare research in the USA. Based on our professional expertise and synthesis of existing literature, we identify two themes in intensive aspects of beef production: areas where policy-based actions are needed and those where additional research is required. For some topics, considerable research informs best practice, yet gaps remain between scientific knowledge and implementation. For example, many of the risk factors and management strategies to prevent respiratory disease are understood, but only used by a relatively small portion of the industry. This is an animal health issue that will require leadership and discussion to gain widespread adoption of practices that benefit cattle welfare. There is evidence of success when such actions are taken, as illustrated by the recent improvements in handling at US slaughter facilities. Our highest priorities for additional empirical evidence are: the effect of technologies used to either promote growth or manage cattle in feedlots, identification of management risk factors for disease in feedlots, and management decisions about transport (rest stops, feed/water deprivation, climatic conditions, stocking density). Additional research is needed to inform science-based recommendations about environmental features such as dry lying areas (mounds), shade, water and feed, as well as trailer design.

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Feeding zilpaterol hydrochloride is associated with decreased dry matter intake shortly after initiation of feeding dependent on season and previous intake1

Cited by 10 publications

References 55 publications

<b>Uso de agonista β-adrenérgico na dieta de bovinos de corte</b>

<b>Uso de agonista β-adrenérgico na dieta de bovinos de corte</b>

Effect of shade on animal welfare, growth performance, and carcass characteristics in large pens of beef cattle fed a beta agonist in a commercial feedlot1

Beef cattle welfare in the USA: identification of priorities for future research

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Feeding zilpaterol hydrochloride is associated with decreased dry matter intake shortly after initiation of feeding dependent on season and previous intake1

Cited by 10 publications

References 55 publications

<b>Uso de agonista &#946;-adrenérgico na dieta de bovinos de corte</b>

<b>Uso de agonista &#946;-adrenérgico na dieta de bovinos de corte</b>

Effect of shade on animal welfare, growth performance, and carcass characteristics in large pens of beef cattle fed a beta agonist in a commercial feedlot1

Beef cattle welfare in the USA: identification of priorities for future research

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<b>Uso de agonista β-adrenérgico na dieta de bovinos de corte</b>

<b>Uso de agonista β-adrenérgico na dieta de bovinos de corte</b>