Feeding interval and use of donor breast milk for very low birthweight infants: A nationwide survey in Japan

Abstract

Most NICUs in Japan use a 3-h feeding interval and do not use DBM for VLBWI. Further prospective studies including multiple confounders are required to clarify the relationship between feeding strategy and the incidence of NEC.

LioNeo project: a randomised double-blind clinical trial for nutrition of very-low-birth-weight infants

“…Eventually, an exploratory laparotomy was performed. The average incidence described in the literature Accepted manuscript ranges from 3•2% to 10•9% 13,14 , but notwithstanding, any NEC event was considered a serious adverse effect.…”

“…Eventually, an exploratory laparotomy was performed. The average incidence described in the literature ranges from 3•2 % to 10•9 % (13,14) , but notwithstanding, any NEC event was considered a serious adverse effect. -Sepsis: the following symptoms can be seen: general symptoms (fever, thermal instability, oedema, malnutrition, poor appearance), GI symptoms (bloating, vomiting, diarrhoea or hepatomegaly), respiratory symptoms (apnoea, dyspnoea, tachypnoea, intercostal retractions, nasal flapping, groaning and cyanosis), renal symptoms (oliguria), cardiovascular symptoms (pallor, mottled, cold or sticky skin, tachycardia, hypotension or bradycardia), central nervous system-related symptoms (irritability, lethargy, tremors, seizures, hyporeflexia, hypotonia, abnormal Moro reflex, irregular breathing, bulging fontanelle and abnormal crying), haematological signs (jaundice, splenomegaly, pallor, petechiae, purpura and bleeding), laboratories examination results (blood count with leukocytosis, left shift or leukopenia, with qualitative changes such as toxic granulation).…”

The legislative framework of donor human milk and human milk banking in Europe

“…However, despite unanimous recommendations, DHM remains underutilized in numerous health systems caring for premature infants (Ashina et al, 2019;Perrin, 2018;Sáenz de Pipaón et al, 2017).…”

“…However, despite unanimous recommendations, DHM remains underutilized in numerous health systems caring for premature infants (Ashina et al, 2019; Perrin, 2018; Sáenz de Pipaón et al, 2017). Uncertainties about the regulatory requirements for handling DHM and the lack of funding have been identified amongst other aspects as barriers for establishing HM banks in neonatal units in Germany (Klotz et al, 2020).…”

Nutrição de recém-nascidos pré-termo de muito baixo peso utilizando um concentrado com liofilizado de leite humano: estudo de fase 1 segurança e tolerabilidade

“…A incidência média descrita na literatura varia de 3,2% a 10,9%, mas, não obstante, qualquer evento de EN foi considerado um efeito adverso grave: (42,43) -ação: suspensão da dieta (mínimo de 1 semana) + antibioticoterapia.…”