Dagan Segal, Assaf Zaritsky, Eyal D. Schejter, Ben-Zion Shilo
Abstract:This work identified a cycle of actin assembly and disassembly in large secretory vesicles of Drosophila salivary glands. Actin disassembly is triggered by actin-dependent recruitment of a RhoGAP protein and is essential for the contractility of the vesicle, leading to content release to the lumen.
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