Journal of Cell Biology volume 217, issue 5, P1815-1826 2018 DOI: 10.1083/jcb.201711006 View full text
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Dagan Segal, Assaf Zaritsky, Eyal D. Schejter, Ben-Zion Shilo

Abstract: This work identified a cycle of actin assembly and disassembly in large secretory vesicles of Drosophila salivary glands. Actin disassembly is triggered by actin-dependent recruitment of a RhoGAP protein and is essential for the contractility of the vesicle, leading to content release to the lumen.