Feedback Control of Juvenile Hormone Synthesis in Cockroaches: Possible Role for Ecdysterone

Stay, Barbara; Friedel, Thomas; Tobe, Stephen S.; Mundall, Eric C.

doi:10.1126/science.207.4433.898

Cited by 100 publications

(22 citation statements)

References 21 publications

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“…The suppression of oocyte maturation by 20HE in P. interpunctella is a direct hormonal effect and does not depend on a secondary endocrine modulator. This is unlike the suppression of ovarian growth by 20HE in the monarch butterfly, Dumus ptexippus [24], the milkweed bug, Oncopeltus fasciafus [25,26], and the cockroach, Diplopteru punctata [27,28] in which 20HE-suppressed ovarian growth is rescuable by treatment with JH. In both 0. fusciatus [25,26] and D.…”

Section: Discussionmentioning

confidence: 51%

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Ecdysteroids control vitellogenesis and egg maturation in pharate adult females of the Indianmeal moth, Plodia interpunctella

Shirk

Bean

Brookes

1990

Arch Insect Biochem Physiol

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(D. WB., V.J.B.) Vitellogenesis occurs during the late pharate adult stage in the lndianmeal moth, Plodia interpunctella. Repeated treatment of pharate adult females with doses of 20-hydroxyecdysone (20HE) from 10 to 250 ng per pupa suppressed oocyte growth and inhibited yolk protein accumulation in the oocytes. Treatment of the pharate adults with a biologically inactive ecdysteroid analogue, 22-isoecdysone, had no effect on egg maturation or yolk protein accumulation. The hormonal action of 20HE was not through the inhibition of the corpora allata or juvenile hormone levels, because treatment with a juvenile hormone analogue did not reverse the inhibition by 20HE treatment. Exposure of early vitellogenic ovaries to 20HE in organ cultures in vitro showed that 20HE had a direct effect on the ovarian synthesis of YP2. At 20HE concentrations below 10 nM, YP2 synthesis was minimal, at 10 nM 20HE YP2 synthesis was maximal, and at concentrations higher than 10 nM YP2 synthesis was suppressed to 35% of the maximal level. Synthesis of most other ovarian proteins remained constant with the changing 20HE concentrations. Ovarian RNA from treated females translated in a reticulocyte lysate demonstrated that the hormonal effect of 20HE on the ovarian tissues was on the specific accumulation of translatable YP2 transcript as well as transcripts for a few other polypeptides. This study shows that 20HE controls the rate of egg development during metamorphosis and that declining titers of 20HE regulate the expression of adult genes.

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Section: Discussionmentioning

confidence: 51%

“…punctatu [27,28], the effect of 20HE was due to an inhibition of corpora allata activity. The 20HE suppression of ovarian growth in P. interpunctella could not be rescued by concomitant treatment with a JHA and is therefore probably not mediated through inhibition of the corpora allata activity.…”

Section: Discussionmentioning

confidence: 89%

Ecdysteroids control vitellogenesis and egg maturation in pharate adult females of the Indianmeal moth, Plodia interpunctella

Shirk

Bean

Brookes

1990

Arch Insect Biochem Physiol

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“…1A). In D. punctata, inactive CA glands of an adult female transplanted into an adult male become active and continue to synthesize JH at high rates (Stay et al, 1980). But, if the CA glands are transplanted together with nearly mature ovaries into males, they remain inactive .…”

Section: Ovarian Inhibition Of Growth Of Ca Cellsmentioning

confidence: 98%

Cell size control by ovarian factors regulates juvenile hormone synthesis in corpora allata of the cockroach,

Chang

Tsai

Yang

et al. 2005

Insect Biochemistry and Molecular Biology

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“…In several species of viviparous cockroaches ovarian ecdysteroids participate in regulating the rates of juvenile hormone synthesis by the corpora allata [28,29,30]. In the house cricket, A. domesticus, the action of 20-hydroxyecdysone on the growth of terminal oocytes has been said to be independent of corpora allata [28][29][30]. In the house cricket, A. domesticus, the action of 20-hyrelease of juvenile hormones by corpora allata in these animals [31].…”

Section: Organ Development and Egg Production In Femalesmentioning

confidence: 99%

Effects of exogenous ecdysteroids on reproduction in crickets,Gryllus bimaculatus

Behrens

Hoffmann

1983

International Journal of Invertebrate Reproduction

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Adult field crickets, Gryllus bimaculatus, with a low endogenous moulting hormone titre (animals reared at constant 20°C) were injected with ecdysone and 20-hydroxyecdysone. Repeated injections of 2-5 pgjfemale caused an increase in ovarian fresh weight and stimulated oviposition. The response to exogenous moulting hormones was shown to be dose dependent. In adult males injections of moulting hormones as well as ringer solution lowered the total number of spermatophores.

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Feedback Control of Juvenile Hormone Synthesis in Cockroaches: Possible Role for Ecdysterone

Cited by 100 publications

References 21 publications

Ecdysteroids control vitellogenesis and egg maturation in pharate adult females of the Indianmeal moth, Plodia interpunctella

Ecdysteroids control vitellogenesis and egg maturation in pharate adult females of the Indianmeal moth, Plodia interpunctella

Cell size control by ovarian factors regulates juvenile hormone synthesis in corpora allata of the cockroach,

Effects of exogenous ecdysteroids on reproduction in crickets,Gryllus bimaculatus

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