Abstract:Background: The aim of this study was to monitor the impact of a preoperative diet and bariatric surgery on the bacterial gut microbiota composition and functionality in severe obesity and to compare sleeve gastrectomy (SG) versus Roux-en-Y gastric bypass (RYGB). The study also aimed to incorporate big data analysis for the omics results and machine learning by a Lasso-based analysis to detect the potential markers for excess weight loss.Methods: Forty patients who underwent bariatric surgery were recruited (1… Show more
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