Fecal Lipid Excretion after Consumption of a Black Tea Polyphenol Containing Beverage–Randomized, Placebo-Controlled, Double-Blind, Crossover Study–

Abstract

Obesity is a serious medical condition worldwide. Inhibition of lipid absorption is very important in preventing obesity. In a previous study, we found that postprandial elevation of triacylglycerol was suppressed by the intake of black tea polyphenol (BTP). We also reported that BTP caused lipid excretion into feces in an animal study. The present study is a clinical trial that examined lipid excretion. In this randomized, placebo-controlled, double-blind, crossover study, in the first test period participants were asked to drink either a beverage containing 55 mg BTP or a control beverage without BTP 3 times a day for 10 d. After an 11-d interval, for the second test period, they then drank the alternate test beverage 3 times a day for 10 d. During the test periods, the participants were asked to eat meals standardized according to calorie and fat content. Stool samples were obtained during the last 3 d of each test period for fecal lipid measurements. Total lipid excretion increased from 5.51 1.73 to 6.87 1.91 g/3 d after BTP intake in comparison with intake of the control beverage. These results indicated that BTP increased lipid excretion.

Screening Camelia sinensis Germplasm Against Grey Leaf Blight of Tea

“…It contains polyphenols and other metabolites, with anti-carcinoma (Wang and Bachrach, 2002;Zhang et al, 2012), anti-oxidative (Rietveld and Wiseman, 2003;Fatima and Rizvi, 2015) and anti-arteriosclerosis (Lee et al, 2015) properties. These polyphenols are also reported to be effective for the prevention of Alzheimer's and Parkinson diseases (Mandel, Amit, Weinreb, Reznichenko, and Youdim, 2008;Anandhan, Tamilselvam, Radhiga, Rao, and Essa, 2012) and for their anti-obesity effects in human and animals (Zhong, Furne, and Levitt, 2006;Ashigai et al, 2016).…”

Effects Of Tea Consumption On Measures Of Cardiovascular Disease: A Systematic Review Of Meta-Analysis Studies And Randomised Controlled Trials

“…Green tea appears to be more strongly related to reduced total and LDL cholesterol, as evidenced by a large number of metaanalytical publications [22,23,[36][37][38]. For black tea those with a higher cardiovascular risk appear to have more benefit [11] with indications from RCTs suggesting that black tea could reduce triglyceride levels, alter body fat distribution and increase fat excretion [6,40,44]. For black tea there is evidence that this can improve FMD and exhibit vascular protective properties that could be of clinical relevance [48,49,53].…”

“…Bahorun et al [56] hip ratio indicating improved body fat distribution [6]. A small trial comprised of two 10-day intervention periods found that the ingestion of black tea polyphenols (55 mg as a beverage) three times daily increased faecal lipid excretion [40]. Other work using Goishi tea (122 mg polyphenols) found this to increase HDL cholesterol and reduce elevations in triglycerides, especially amongst those with a BMI <25 kg/m 2 after 12 weeks of drinking this [39].…”

“…Eight RCTs examined the effects of tea interventions on cholesterol levels, lipid profile and distribution [6,[39][40][41][42][43][44]. In most studies 3 to 5 cups of tea were ingested daily [6,41,42,44].…”

“…Ashigai et al [40]; Bohn et al [6]; Bahorun et al [44] Ishida et al [39]; Rafraf et al [41] Cardiovascular function Strong meta-analytical evidence indicates that drinking green tea (1-3 cups daily) could reduce MI and stroke risk. Other works shows 2-3 cups of green or black tea daily could improve endothelial function.…”