Febrile Urinary Tract Infections in 0- to 3-Month-Old Infants: A Prospective Follow-Up Study

Antimicrobial Resistance and Diagnostic Imaging in Infants Younger Than 2 Months Old Hospitalized With a First Febrile Urinary Tract Infection

“…2,10-12,20,21 None of the boys in this study were circumcised at the time of UTI, similar to previous studies. 2,8,11,12,20,21 The mean time of fever duration before admission and after treatment was 1.3 days and 1.3 days, respectively, for the young infant group and 2.1 days and 1.7 days, respectively, for the young children group, similar to the findings of a previous study. 11 The relatively shorter duration of fever before admission and after treatment in the young infant group may be partly explained by parental vigilance and alarm at the presence of fever in younger infants, which prompts the parents/providers to seek care more quickly than that for older children.…”

“…2,11-13 Males predominated (65.7%) in our study, especially in the young infant group (76.3%), in agreement with other reports. 2,11,12,20,21 Phimosis seems to be an important risk factor for UTI in male infants. 2,10-12,20,21 None of the boys in this study were circumcised at the time of UTI, similar to previous studies.…”

“…[29][30][31] E. coli showed a high rate of resistance to ampicillin (75.8%) and TMP/SMX (55.8%) in our study, consistent with previous reports of the rate of resistance to ampicillin (55.0-82.0%) and TMP/SMX (30.0-57.1%). 12,[30][31][32] In contrast, resistance to the firstand third-generation cephalosporins, and aminoglycosides was relatively low in this study, with resistance rates of 24.2% to cefazolin, 6.9% to ceftriaxone, 13.1% to gentamicin, and 0% to amikacin, in accordance with recent reported resistance rates of 24.0-46.3% to cefazolin, 12.9-24.9% to gentamicin, and 0-1.1% to amikacin in Taiwan. [31][32][33][34] It is important to start empiric treatment of childhood UTI considering not only the most probable uropathogen but also its most likely antimicrobial susceptibility when selecting the antimicrobial agents.…”

“…1 In addition, many published studies on this age group have significant design or reporting flaws that may further cloud the clinical picture and limit their impact. [8][9][10][11][12][13] We examined a defined group of infants ≤2 months of age hospitalized with their first-diagnosed community-acquired febrile UTI and compared them to young children 2-24 months of age on clinical characteristics, laboratory data, uropathogens and antimicrobial Copyright © 2016 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.…”

Évaluation des pratiques de prise en charge des infections urinaires de l’enfant

“…En cas de méningite associée, la céphalosporine choisie devait être le céfotaxime. Protocole en vigueur dans le service de néonatalogie du CHRU de Lille, défini comme le protocole à suivre pour cette étude, en l'absence de consensus national ou international thérapeutique [12,13].…”