Features of Wound Healing in Patients with Neuroendocrine Pathologies

Abstract

This study allows understanding the course of the process of tissue regeneration in the pathology of the nervous and endocrine systems. These systems are closely interconnected. The integrity of their pathogenic actions on the body is called neroendocrinopathies. They affect body tissues and especially the skin epithelium, independently causing dystrophies and changing their healing rate and regeneration of wounds received during the course of the disease. The wound healing rate depends on many factors, such as age, nutritional status and body weight, body immune status, and chronic comorbidities. The endocrine and nervous system disorders affect oxygenation, hormonal imbalance and nutrient supply of local tissues and the whole body. A wide range of diseases in humans, such as atopic dermatitis, psoriasis, herpes zoster, arthritis, diabetes is characterized by a distinct neurogenic and endocrine component. Micro- and macroangiopathy develops, carbohydrate metabolism in tissues suffers and immunity disorders occur. This disrupts the course of the wound healing process and slows down the recovery processes.

Direct Endolymphatic Ozone Therapy in Patients with Diabetic Foot Syndrome: Analysis of the Effectiveness

“…Патогенетические основы применения озонированных растворов в гнойной хирургии обусловлены высокой антимикробной активностью озона, его выраженным антигипоксантным действием, неспецифическим влиянием на иммунную систему организма, а также относительной простотой получения, низкой стоимостью и малым количеством осложнений в процессе лечения [6,7]. Известно, что бактерии и токсины активно распространяются по лимфатическому руслу, поэтому применение методов эндолимфатического введение антибактериальных, дезинтоксикационных и иммунокорригирующих препаратов способствует поддержанию гомеостаза организма [7,8,9].…”