Features of the content of magnesium, selenium, and strontium in the blood components of newborns and mothers at a risk of miscarriage

Abstract

Purpose.This study analyzes changes in the concentration of elements — magnesium, selenium, strontium — in plasma and RBCs of peripheral blood in parturient women with a history of threatened miscarriage and their newborns. In addition, the difference in cell-membrane permeability indices for each element was determined.Characteristics of children and research methods. 97 pairs of full-term newborns and their mothers were under observation. The main cohort (Group 1) consisted of 57 mother–child pairs under a threat of miscarriage. The control group (Group 2) consisted of 40 conditionally healthy pairs. Concentrations of chemical elements were determined in plasma and RBCs using mass spectrometry with inductively coupled plasma. Statistical processing consisted of two stages. Initially, the authors determined parameters with a significant change in the concentration of elements, in the presence of a threat of abortion. Then the values of the relationships between all parameters for each element were calculated.Results.There is an increase in the concentrations of magnesium and selenium in the body of parturient women with a history of threatened miscarriage in comparison with healthy women in labor. The concentration of strontium does not change. In newborns, the concentration of magnesium also increases, and strontium decreases. The concentration of selenium in newborns does not change.Conclusion. The study findings indicate that the threat of termination of the current pregnancy is accompanied by a change in the elemental status of mothers and their newborns.