Features of generation and differentiation of induced pluripotent stem cells into retinal cells for modeling human hereditary diseases
Evgeniy V. Lapshin,
Yulia G. Gershovich,
Ekaterina S. Minskaya
et al.
Abstract:Currently, numerous studies demonstrate the possibility of generating human iPSCs from somatic cells, which ensures the rapid progress of research in human diseases for which there are no relevant animal models or limited access to primary human tissues and cells. The utilization of technology for generation of iPSCs with their subsequent differentiation is, among other things, a promising approach for studying the disease pathogenesis and developing methods for treating optical neuropathies and retinopathy - … Show more
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