Feasibility, utility and symptom impact of modified mindfulness training in sarcoidosis

Abstract

Sarcoidosis is a multisystem disorder characterised by noncaseating granulomatous inflammation of unknown aetiology. It may resolve spontaneously, but ∼30% of patients have progressive disease with significant organ damage [1]. Although any organ is vulnerable, the lungs are frequently involved resulting in shortness of breath and dry cough. Fatigue is an overarching symptom in sarcoidosis, originating from multiple and combined causes of mental fatigue and physical fatigue [2]. This is also true of the psychosocial impact of sarcoidosis, which may include depression, anxiety, isolation and feelings of uncertainty. The prevalence of these factors remains high even for those who achieve clinical remission, resulting in psychological distress and reduced health status [3].

Comprehensive Care for Patients with Sarcoidosis

“…To date, one study analyzed the impact of mindfulness-based exercise therapy on physical and psychological symptoms in sarcoidosis. Even though this was a modified training consisting of only one 45-minute workshop, symptoms significantly decreased after the session [63]. A randomized controlled trial to assess the impact of an online mindfulness-based cognitive behavioral therapy on QoL, fatigue, stress, and anxiety is currently ongoing [64].…”

“…Other causes for dyspnea such as infection or pulmonary hypertension should also be evaluated [12]. Non-pharmacological treatment options include physical training, multidisciplinary pulmonary rehabilitation and potentially cognitive behavioral therapy [58][59][60]63] ( Table 1). Cough is present in up to 53% of sarcoidosis patients [65].…”

“…Further studies regarding antitussive therapy in sarcoidosis are highly needed. [13] Cognitive behavioral therapy [63] Depression and Anxiety…”

“…Antidepressants [13] ** Anxiolytics ** Cognitive behavioral therapy [63] Pulmonary rehabilitation [58] Psychological counselling [46] Small-Fiber Neuropathy…”

The Burden of Neurosarcoidosis: Essential Approaches to Early Diagnosis and Treatment

“…Furthermore, mindfulness-based exercise interventions or cognitive rehabilitation could also improve memory and concentration, as already reported in cancer. 115,116 Moreover, in a small study in sarcoidosis patients a reduction in fatigue was seen after a 45-minute program of mindfulnessbased exercise interventions. 115 Further studies to assess the long-term benefits of these interventions in sarcoidosis patients are needed.…”