Feasibility trial of weighted blankets as an intervention for emergence delirium in postoperative pediatric patients

Eull, Donna; Zachrison, Brenda; Nickel, Amanda

doi:10.1016/j.pedn.2021.11.022

Cited by 6 publications

(4 citation statements)

References 31 publications

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“…One exploratory study showed that parents of children with CHARGE syndrome found weighted blankets slightly effective in improving children’s sleep problems ( 24 ). The positive effects of weighted blankets were also found in children under general anesthesia, indicating that weighted blankets can be safely used for hospitalized children ( 46 ). Another crossover randomized controlled trial in 16 infants with neonatal withdrawal syndrome (NAS) found no adverse events during 67 30-minute sessions with weighted blanket, confirming the safety, feasibility, and efficacy of weighted blanket in reducing NAS symptoms ( 47 ).…”

Section: Resultsmentioning

confidence: 93%

The effect of weighted blankets on sleep and related disorders: a brief review

Yu,

Yang,

Sun

et al. 2024

Front. Psychiatry

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BackgroundSleep disorders such as insomnia can lead to a range of health problems. The high risk of side effects and drug abuse of traditional pharmacotherapy calls for a safer non-pharmacotherapy.AimsTo examine the use and efficacy of weighted blankets in improving sleep and related disorders in different populations and explore the possible mechanisms.MethodsA literature search was conducted using PubMed, Embase, Web of Science, MEDLINE, Cochrane Library and CNKI databases. Eligible studies included an intervention with weighted blankets and outcomes covering sleep and/or related disorders (behavioral disturbance, negative emotions and daytime symptoms). Studies using other deep pressure, compression, or exercise-related interventions were excluded.ConclusionsMost of the included studies showed that weighted blankets could effectively improve sleep quality and alleviate negative emotions and daytime symptoms in patients with sleep disorders, attention deficit hyperactivity disorder, autism spectrum disorder, and other related disorders, with a possible mechanism of deep pressure touch.RecommendationsWeighted blankets might be a promising tool for sleep interventions among individuals with sleep disorders in clinical settings. More high-quality and large-scale randomized controlled trials are needed to further validate the safety and efficacy of weighted blankets and explore precise mechanisms.

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Section: Resultsmentioning

confidence: 93%

The effect of weighted blankets on sleep and related disorders: a brief review

Yu,

Yang,

Sun

et al. 2024

Front. Psychiatry

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“…In the case of ED (PAED score ≥10 but FLACC <4), initial comfort measures will have been taken. Initial comfort measures include the application of weighted blankets or the provision of gentle and sustained touch by a PACU nurse ( Eull et al, 2022 ; Kim et al, 2024 ). If these are ineffective, 1 mg kg -1 propofol will be administered.…”

Section: Methodsmentioning

confidence: 99%

The effect of remimazolam-based total intravenous anesthesia versus sevoflurane-based inhalation anesthesia on emergence delirium in children undergoing tonsillectomy and adenoidectomy: study protocol for a prospective randomized controlled trial

Ma,

Cai,

Zhong

et al. 2024

Front. Pharmacol.

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Background: Remimazolam, a new ultrashort-acting benzodiazepine, is becoming increasingly applied in general anesthesia. This study is designed to investigate the effect of remimazolam-based total intravenous anesthesia and sevoflurane-based inhalation anesthesia on emergence delirium in pediatric tonsillectomy and adenoidectomy.Methods and analysis: This is a monocentric, prospective, randomized, double-blind clinical trial. A total of 90 pediatric patients will be randomized to receive remimazolam-based total intravenous anesthesia (remimazolam group, n = 45) or sevoflurane-based inhalation anesthesia (sevoflurane group, n = 45). The primary outcome will be the incidence of emergence delirium, which will be evaluated using the Pediatric Anesthesia Emergence Delirium (PAED) scale. The secondary outcomes include the extubation time, recovery time, behavior change using the post-hospitalization behavior questionnaire for ambulatory surgery (PHBQ-AS), and adverse events.Ethics and dissemination: This study has been approved by the Institutional Review Board (IRB) of the Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University (2023-K-262-02).Clinical trial registration:ClinicalTrials.gov, identifier NCT06214117.

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“…These include educational interventions for parents, children, and healthcare professionals [ 29 – 31 ], playing music and mothers’ voices for children [ 32 – 34 ], and providing weighted blankets as an intervention [ 35 ]. Furthermore, multicomponent interventions have been explored in children [ 36 ].…”

Section: Introductionmentioning

confidence: 99%

Non-pharmacological interventions for delirium in the pediatric population: a systematic review with narrative synthesis

Kim,

Jeong,

Choi

2024

BMC Pediatr

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Background Delirium is a serious complication experienced by hospitalized children. Therefore, preventive management strategies are recommended for these patients. However, comprehensive analyses of delirium interventions in children remain insufficient. Specifically, this systematic review aimed to summarize non-pharmacological interventions for pediatric delirium, addressing the urgent need for a comprehensive understanding of effective strategies. We also explored frequently measured outcome variables to contribute evidence for future research on delirium outcomes in children. Methods This systematic review searched articles from PubMed, Web of Science, Cumulative Index to Nursing and Allied Health Literature, and Excerpta Medica databases. The eligibility criteria were formed under the population, intervention, comparator, outcome, and study design framework. Studies were included if they involved (1) children aged under 18 years receiving hospital care, (2) non-pharmacological delirium interventions, (3) comparators involving no intervention or pharmacological delirium interventions, and (4) outcomes measuring the effectiveness of non-pharmacological delirium interventions. Only peer-reviewed articles published in English were included. Results Overall, 16 studies were analyzed; of them, 9 assessed non-pharmacological interventions for emergence delirium and 7 assessed interventions for pediatric delirium. The intervention types were grouped as follows: educational (n = 5), multicomponent (n = 6), and technology-assisted (n = 5). Along with pediatric and emergence delirium, the most frequently measured outcome variables were pain, patient anxiety, parental anxiety, pediatric intensive care unit length of stay, agitation, analgesic consumption, and postoperative maladaptive behavior. Conclusions Non-pharmacological interventions for children are effective treatments without associated complications. However, determining the most effective non-pharmacological delirium intervention for hospitalized children based on current data remains challenging.

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Feasibility trial of weighted blankets as an intervention for emergence delirium in postoperative pediatric patients

Cited by 6 publications

References 31 publications

The effect of weighted blankets on sleep and related disorders: a brief review

The effect of weighted blankets on sleep and related disorders: a brief review

The effect of remimazolam-based total intravenous anesthesia versus sevoflurane-based inhalation anesthesia on emergence delirium in children undergoing tonsillectomy and adenoidectomy: study protocol for a prospective randomized controlled trial

Non-pharmacological interventions for delirium in the pediatric population: a systematic review with narrative synthesis

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