Feasibility Study of Computational Fluid Dynamics Simulation of Coronary Computed Tomography Angiography Based on Dual-Source Computed Tomography

Lü, Jing; Yu, Jie; Shi, Heshui

doi:10.14740/jocmr2623w

Cited by 6 publications

(3 citation statements)

References 15 publications

(13 reference statements)

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“…Analysis Sensor Structure using CFD Computational fluid dynamics (CFD) is an effective and powerful tool that stimulates fluid flow numerically [10]. Besides that, computational fluid dynamics (CFD) is an interdisciplinary tool that is related to both the computer technology and fluid physics [11]. Capacitive based flow sensor needs the CFD simulation approach to get an effective simulation and to produce the best result especially on drag force acting on the different types of structures.…”

Section: Design and Methodologymentioning

confidence: 99%

The Effect of Sensor Structure and Coplanar Electrode for Capacitive Based Flow Sensor

Nawi¹,

Azeman²,

Razak³

2019

IJRTE

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This paper presents the analysis of the capacitive based flow sensor using computational fluid dynamic (CFD) and mathematical equation approach. The CFD simulations for different types of sensor structure were carried out. Pressure and velocity of the fluid were varied in order to study the hydrodynamic parameter such as displacement and drag force. For the coplanar electrode, width of electrode and half gap between electrodes were varied for capacitive response using mathematical approach. Based on the simulation, the displacement of the dome increases as the pressure increases. The result shows that the most suitable thickness of the dome is 0.1 mm based on the displacement and the strain. Meanwhile for the coplanar electrode, the width and half gap showed a significant effect on the capacitance response.

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Section: Design and Methodologymentioning

confidence: 99%

The Effect of Sensor Structure and Coplanar Electrode for Capacitive Based Flow Sensor

Nawi¹,

Azeman²,

Razak³

2019

IJRTE

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“…Each 3D-reconstruction was converted to a tetrahedral mesh with a 5-layer prism layer at the boundary using the open-source software FreeCAD (https:// www.freecadweb.org/), with a maximum element size of 0.1-0.2 mm in the stenotic lumen and of 0.35-0.5 mm in the reference lumen. Mesh independence test at similar scale was conducted in a previous study validating the feasibility of WSS simulation using CCTA images (21).…”

Section: A B C Dmentioning

confidence: 99%

Validation of hemodynamic stress calculation in coronary computed tomography angiography versus intravascular ultrasound

Ding¹,

Liu²,

Wang³

et al. 2023

Quant Imaging Med Surg

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Background: Development in computational fluid dynamics and 3D construction could facilitate the calculation of hemodynamic stresses in coronary computed tomography angiography (CCTA). However, the agreement between CCTA derived stresses and intravascular ultrasound/intravascular coronary angiography (IVUS/ICA)-derived stresses remains undetermined. Thus, the purpose of this study is to investigate if CCTA can serve as alternative to IVUS/ICA for hemodynamic evaluation.Methods: In this retrospective study, 13 patients (14 arteries) with unstable angina who underwent both CCTA and IVUS/ICA at an interval of less than 7 days were consecutively included at the Chinese PLA General Hospital within the year of 2021. Slice-level minimal lumen area (MLA), percent area stenosis, velocity, pressure, Reynolds number, wall shear stress (WSS) and axial plaque stress (APS) were determined by both modalities. The agreement between CCTA and IVUS/ICA was assessed using the intraclass correlation coefficient (ICC), Pearson's correlation coefficient and Bland-Altman analysis.Results: CCTA overestimated the degree of area stenosis (50.22%±16.15% vs. 36.41%±19.37%, P=0.004) with the MLA showing no significant difference (5.81±2.24 vs. 6.72±2.04 mm 2 , P=0.126). No statistical difference was observed in WSS (6.57±6.26 vs. 5.98±5.55 Pa, P=0.420) and APS (16.03±1,159.45 vs. −1.27±890.39 Pa, P=0.691) between CCTA and IVUS. Good correlation was found in velocity (ICC: 0.796, 95% CI: 0.752-0.833), Reynolds number (ICC: 0.810, 95% CI: 0.768-0.844) and WSS (ICC: 0.769, 95% CI: 0.718-0.810), while the ICC of APS was (ICC: 0.341, 95% CI: 0.197-0.458), indicating a relatively poor correlation.Conclusions: CCTA can serve as a satisfactory alternative to the reference standard, IVUS/ICA in morphology simulation and hemodynamic stress calculation, especially in the calculation of WSS.

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“…ПНС -это тангенциальная сила, действующая на поверхность эндотелия, которая возникает в результате трения текущей крови [14]. Данная величина пропорциональна градиенту скорости (dv/dy) около стенки сосуда (эндотелия), т. е. насколько быстро увеличивается скорость кровотока при перемещении из точки на эндотелии в смежную точку в перпендикулярном направлении, от эндотелия к центру сосуда [15,16]. Отсюда следует, что низкие значения ПНС связаны с низкими локальными скоростями и, следовательно, с большим временем пребывания крови в контакте с эндотелием.…”

Section: коронарный кровоток и пристеночное напряжение сдвигаunclassified

Features of local hemodynamics and the formation of atherosclerotic lesions in coronary artery bifurcation

Khelimskii¹,

Бадоян²,

Эралиев³

et al. 2020

Russ J Cardiol

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Процесс формирования атеросклеротической бляшки в коронарных артериях носит сложный, многофакторный характер, зависящий не только от традиционных факторов риска сердечно-сосудистых заболеваний, но и от особенностей локальной гемодинамики. Атеросклеротические бляшки часто возникают в области бифуркации артерий -там, где кровоток неравномерен. В таких условиях пристеночное напряжение сдвига становится ключевым фактором развития, распространения и прогрессирования атеросклеротической бляшки. Кроме того, ряд факторов, как индивидуальная геометрия бифуркации, имплантация коронарного стента, техника имплантации могут существенно влиять на показатели напряжения сдвига и тем самым влиять на патофизиологию коронарного атеросклероза.

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Feasibility Study of Computational Fluid Dynamics Simulation of Coronary Computed Tomography Angiography Based on Dual-Source Computed Tomography

Cited by 6 publications

References 15 publications

The Effect of Sensor Structure and Coplanar Electrode for Capacitive Based Flow Sensor

The Effect of Sensor Structure and Coplanar Electrode for Capacitive Based Flow Sensor

Validation of hemodynamic stress calculation in coronary computed tomography angiography versus intravascular ultrasound

Features of local hemodynamics and the formation of atherosclerotic lesions in coronary artery bifurcation

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